茶基纳米材料的制备及其在药物递送中应用的研究进展OA
Research Progress in the Preparation of Tea-Based Nanomaterials and Their Application in Drug Delivery
茶叶中的多种活性成分具有良好的还原配位、生物相容及界面作用,是制备药物递送纳米材料的理想载体.本文在综述茶叶主要活性成分性能与缺陷的基础上,总结了原位生长、配位组装、共混交联、静电组装等茶基纳米材料主流制备技术的反应机制、技术特点,以及所制纳米载体在提升活性成分稳定性、实现药物缓释控释与靶向转运方面的应用效果.指出未来应进一步优化工艺,完善靶向修饰及智能响应设计,推动茶基纳米材料在药物递送中的产业化应用.
Various bioactive constituents in tea have been found to possess favorable reduction,coordination,biocompatibility and interfacial properties,making them ideal nanocarriers for preparing drug delivery nanomaterials.On the basis of reviewing the performances and drawbacks of primary tea-derived bioactive substances,the reaction mechanisms,technical features of dominant fabrication approaches including in situ growth,coordination self-assembly,blending crosslinking and electrostatic assembly were summarized in this paper,together with the applications of resultant nanocarriers in enhancing ingredient stability as well as realizing sustained,controlled and targeted drug delivery.It was proposed that fabrication procedures,targeted modification and stimuli-responsive design should be further optimized to promote the industrialized application of tea-based nanomaterials in drug delivery.
林燕萍;杨陈;程蓓
江西服装学院,江西 南昌 330201江西服装学院,江西 南昌 330201江西服装学院,江西 南昌 330201
农业科技
茶叶活性成分纳米材料制备药物递送
teaactive ingredientsnanomaterialspreparationdrug delivery
《茶叶科学》 2026 (4)
571-584,14
江西服装学院横向项目(JFHX202521)
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