效应面法结合BP神经网络模型优化五冬果茶提取工艺OA
Optimization of Wudong fruit tea extraction process using RSM and BP neural network model approach
为了优化五冬果茶的最佳提取工艺,根据关键质量属性、关键工艺参数的筛选结果,选择对提取工艺影响较大的溶剂倍数、提取时间为考察因素,以干膏率、补骨脂素含量、感官评价为评价指标.通过对比AHP加权法、CRITIC加权法、AHP-CRITIC混合加权法,明确三种加权方法在本试验中的适用性,最终确定使用AHP-CRITIC混合加权法确定各评价指标的权重.先采用星点设计-效应面法优化工艺,再建立BP神经网络模型对星点设计-效应面法的结果进行预测并确定最佳条件.最佳工艺为:处方量药材用水煎煮提取2次,每次加 13 倍水、提取 60 min,过滤即得.星点设计-效应面法结合BP神经网络优化的五冬果茶提取工艺的稳定性和重复性良好,可为其进一步的研究和开发提供科学依据.
To optimize the extraction process of Wudong fruit tea,based on preliminary screening,the water-to-material ration and extraction time were selected as key independent variables,with dry extract yield,psoralen content,and sensory evaluation serving as dependent evaluation indices.A comparative analysis was conducted on the applicability of three weighting method(AHP,CRITIC,and AHP-CRITIC hybrid),the AHP-CRITIC hybrid weighting method was ultimately selected to determine the index weights.A star-point design combined with response surface methodology(RSM)was employed for optimization of the extraction process,followed by a backpropagation(BP)neural network model to predict and validate the optimal conditions.The optimal extraction parameters were determined as follows:the prescribed medicinal materials was extracted with boiled water at 13-fold amount twice,and 60 minutes of extraction time(per cycle,for two cycles),followed by filtration.The integration of the star-point design-RSM and BP neural network demonstrated robust stability and reproducibility in optimizing the extraction of Wudong fruit tea,providing a scientific foundation for the optimized method in future research.
曾大洋;罗渝欢;李业航;覃柳娇;王一垚;范丽丽;黄俊善;陈卫卫
广西中医药大学药学院,南宁 530200||广西高校中药制剂共性技术与研发重点实验室,南宁 530200广西中医药大学药学院,南宁 530200||广西高校中药制剂共性技术与研发重点实验室,南宁 530200广西中医药大学药学院,南宁 530200||广西高校中药制剂共性技术与研发重点实验室,南宁 530200广西中医药大学药学院,南宁 530200||广西高校中药制剂共性技术与研发重点实验室,南宁 530200广西中医药大学药学院,南宁 530200||广西高校中药制剂共性技术与研发重点实验室,南宁 530200广西中医药大学药学院,南宁 530200广西中医药大学药学院,南宁 530200广西中医药大学药学院,南宁 530200||广西高校中药制剂共性技术与研发重点实验室,南宁 530200
轻工纺织
五冬果茶提取工艺优化星点设计-效应面法AHP-CRITIC混合加权法BP神经网络
Wudong fruit teaextraction process optimizationstar-point design-response surface methodologyAHP-CRITIC hybrid weighting methodBP neural network
《中国食品添加剂》 2026 (1)
23-32,10
广西研究生教育创新计划项目2023年广西学位与研究生教育改革课题(编号JGY2023179)
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