点刺金津、玉液、咽后壁治疗脑梗死急性期吞咽功能障碍的疗效分析OA
Efficacy Analysis of Pricking Jinjin,Yuye,and Posterior Pharyngeal Wall in Treating Swallowing Dysfunction in Acute Cerebral Infarction
目的:观察点刺金津、玉液、咽后壁治疗脑梗死急性期吞咽功能障碍的效果.方法:纳入2024 年3 月—2025 年3 月北京市鼓楼中医医院诊疗的脑梗死急性期吞咽功能障碍患者88 例,随机分为常规治疗组(44 例,常规治疗)、点刺组(44 例,常规治疗+点刺),比较点刺组与常规治疗组吞咽功能、生活质量、营养指标、神经损伤标志物水平,对两组进行临床疗效评估,并记录两组吞咽功能障碍相关并发症发生情况.结果:治疗后点刺组标准吞咽功能量表(SSA)、洼田饮水试验(WST)评分低于常规治疗组(P<0.01),吞咽生命质量量表(SWAL-QOL)评分高于常规治疗组(P<0.01);治疗后点刺组血清白蛋白(ALB)、前白蛋白(PAB)水平高于常规治疗组(P<0.01);治疗后点刺组血清中枢神经特异性蛋白(S100β)、神经元特异性烯醇化酶(NSE)水平低于常规治疗组(P<0.01);点刺组总有效率高于常规治疗组(P<0.05);点刺组吸入性肺炎、窒息等并发症总发生率低于常规治疗组(P<0.05).结论:点刺金津、玉液、咽后壁治疗脑梗死急性期吞咽功能障碍可促进患者吞咽功能恢复,减轻其神经功能损伤,并能提升患者营养指标、生活质量,减少并发症.
Objective:To observe the effect of acupuncture of Jinjin,Yuye and posterior pharyngeal wall in the treatment of swallowing dysfunction in the acute phase of cerebral infarction.Methods:The study started and ended from March 2024 to March 2025,88 patients with swallowing dysfunction in the acute phase of cerebral infarction admitted to Beijing Gulou Hospital of Traditional Chinese Medicine were included and randomly divided into two groups,44 cases in each group:acupuncture group(conventional treatment+acupuncture)and conventional treatment group(conventional treatment).The swallowing function,quality of life,nutritional indicators,and nerve injury marker levels of the acupuncture group and the conventional treatment group were evaluated/measured and compared,and the efficacy was evaluated,and the occurrence of complications related to swallowing dysfunction was recorded.Results:After treatment,the Standardized Swallowing Assessment(SSA)and Water Swallow Test(WST)scores of the acupuncture group were lower than those of the conventional treatment group,and the Swallowing Quality of Life Scale(SWAL-QOL)score was higher than that of the conventional treatment group(P<0.01).After treatment,the serum albumin(ALB)and prealbumin(PAB)levels of the acupuncture group were higher than those of the conventional treatment group(P<0.01).After treatment,the serum soluble protein-100β(S100β)and neuron specific enolase(NSE)levels of the acupuncture group were lower than those of the conventional treatment group(P<0.01).The total effective rate of the acupuncture group was higher than that of the conventional treatment group(P<0.05).The total incidence of complications such as aspiration pneumonia and suffocation in the acupuncture group was lower than that in the conventional treatment group(P<0.05).Conclusion:Acupuncture of Jinjin,Yuye and the posterior pharyngeal wall to treat swallowing dysfunction in the acute phase of cerebral infarction can promote the recovery of patients'swallowing function,reduce their neurological damage,improve their nutritional indicators and quality of life,and reduce complications.
李琰琴;王乐;耿洪娇;李曌嫱
北京市鼓楼中医医院针灸科,北京 100009北京市鼓楼中医医院针灸科,北京 100009北京市鼓楼中医医院针灸科,北京 100009北京市鼓楼中医医院针灸科,北京 100009
医药卫生
脑梗死吞咽功能障碍点刺营养状况神经损伤标志物随机对照
Cerebral infarctionSwallowing dysfunctionAcupunctureNutritional statusNerve damage markersRandomized controlled
《中医药学报》 2026 (10)
54-58,5
首都卫生发展科研专项项目(首发2024-2-7012)
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