氧化苦参碱调控肝脏脂质代谢的作用机制及其在动物生产中的应用OA

Oxymatrine is a natural alkaloid derived from plants of the Sophora genus within the Fabaceae family,which exhibits multiple pharmacological activities including anti-inflammatory,antioxidant,and anti-hepatic fibrosis effects.Through multi-target mechanisms,it effectively inhibits hepatic lipid synthesis while promoting oxidative breakdown,thereby improving hepatic lipid metabolism disorders and fat deposition.Currently,oxymatrine has been preliminarily applied in aquaculture and poultry farming for antibacterial,antiparasitic,and immunomodulatory purposes.However,research on its role in regulating lipid metabolism in livestock and poultry livers remains limited,and its safety across different animal species requires systematic evaluation.This review summarizes the mechanism by which oxymatrine regulates liver lipid metabolism and the research progress of its application in animal production,providing theoretical reference for the application of oxymatrine in the fields of animal nutrition and health.