不同CT血流储备分数分层冠心病患者平板运动试验参数特征分析OA

Objective To analyze the characteristics of treadmill exercise test(TET)parameters in patients with coronary heart disease(CHD)stratified by different levels of CT-derived fractional flow reserve(CT-FFR),and to explore their correlations with CT-FFR.Methods A total of 92 CHD patients who consecutively underwent coronary computed tomography angiography(CCTA),CT-FFR calculation and TET in our hospital from January 2021 to December 2025 were retrospectively enrolled.Based on the lowest CT-FFR value of the main coronary arteries,patients with CT-FFR ≤ 0.80 were assigned to the ischemia group(65 cases),and those with CT-FFR＞0.80 were assigned to the non-ischemia group(27 cases).The positive rate of TET,exercise duration,peak metabolic equivalents(METs)and Duke score were compared between the two groups,and the correlations between these parameters and CT-FFR were analyzed.Results The positive rate of TET in the ischemia group was 52.31％,which showed no statistically significant difference compared with 40.74％in the non-ischemia group(P＞0.05).The exercise duration,peak METs and Duke score in the ischemia group were(393.34±138.22)s,8.56±2.41 and(2.07±6.19)points respectively,and there were no statistically significant differences compared with(422.30±136.33)s,9.29±2.41 and(3.68±5.78)points in the non-ischemia group(P＞0.05).Spearman rank correlation analysis showed that CT-FFR was weakly positively correlated with exercise duration,peak METs and Duke score(rs=0.259,0.229,0.226,all P＜0.05).Conclusions CHD patients with decreased CT-FFR show a downward trend in exercise tolerance and Duke score.The combination of multiple TET parameters can complementarily reflect coronary functional ischemia from the perspectives of exercise tolerance and electrocardiographic changes,but a single parameter has limited discriminative ability for different CT-FFR strata.