超声脐动脉、大脑中动脉血流参数联合脑胎盘比值对胎儿生长受限的诊断价值OA

Objective To explore the diagnostic value of ultrasound blood flow parameters of umbilical artery(UA)and middle cerebral artery(MCA)combined with cerebroplacental ratio(CPR)for fetal growth restriction(FGR).Methods A total of 78 pregnant women with confirmed FGR who underwent prenatal examination in our hospital from January 2025 to February 2026 were retrospectively enrolled as the study group,and another 70 healthy pregnant women with normal prenatal examination and normally developed fetuses during the same period were selected as the control group.Color Doppler ultrasonography was performed on pregnant women in both groups to measure the pulsatility index(PI),resistance index(RI),peak systolic velocity to end-diastolic velocity ratio(S/D)of fetal UA and MCA,and the CPR was calculated.All blood flow parameters and CPR were compared between the two groups,and receiver operating characteristic(ROC)curves were plotted to analyze the diagnostic efficacy of each indicator alone and in combination for FGR.Results The UA-PI,UA-RI and UA-S/D of fetuses in the study group were significantly higher than those in the control group,while MCA-PI,MCA-RI,MCA-S/D and CPR were significantly lower than those in the control group(P＜0.05).ROC curve analysis showed that the area under the curve(AUC)of combined diagnosis of FGR using UA/MCA blood flow parameters(UA-PI,UA-RI,UA-S/D,MCA-PI,MCA-RI,MCA-S/D)and CPR was 0.981,which was higher than that of each single indicator.Conclusions Fetuses with growth restriction present significant abnormalities in UA and MCA blood flow parameters as well as decreased CPR.The combination of UA/MCA blood flow parameters and CPR has high diagnostic value for FGR,which helps improve the detection rate of FGR during pregnancy and provides imaging reference for early identification and clinical intervention of FGR.