母猪子宫容受性研究进展OA

The uterus is a key component of the sow's reproductive system,and its receptivity status is coordinately regulated by multiple factors including hormones,immunity,nutrition,and the environment.Within a strictly defined temporal window,the uterus establishes and maintains a receptive phenotype;this condition constitutes a prerequisite for successful embryo implantation and the progression of gestation.Compromised uterine receptivity directly decreases implantation efficiency and consequently reduces litter size.This review systematically delineate the histo-architectural basis underlying uterine receptivity in sows and dissect the molecular circuitry that integrates hormonal orchestration,cell-adhesion crosstalk,immune tolerance,and non-coding-RNA-mediated epigenetic regulation,aiming to provide a comprehensive mechanistic portrait of the establishment and fine-tuning of porcine uterine receptivity.A comprehensive and in-depth understanding of uterine receptivity in sows enables multidimensional optimization of reproductive management strategies,providing both theoretical foundations and novel approaches for improving porcine reproductive efficiency.