蛋鸡超长产蛋期性状的遗传调控及品种培育进展OA

Breeding new laying hen varieties with an ultra-long production cycle is a crucial strategic measure to cope with global population growth,rising protein demand,and to achieve of sustainable livestock production.Here,we systematically reviewed the research progress in the genetic dissection and breeding technologies for traits related to the ultra-long production cycle in laying hens.In terms of genomic resources,breakthroughs in the chicken pangenome and telomere-to-telomere(T2T)assembly technologies have significantly expanded the scope of genetic variation detection,identified a large number of previously unannotated novel sequences and structural variations.The integration of multi-omics databases has further laid a solid foundation for deciphering underlying regulatory networks.Regarding the genetic dissection of key traits,the combined application of genome-wide association studies(GWAS)and multi-omics approaches to core phenotypes—including egg production,egg quality,feed efficiency,and metabolic health—has revealed key regulatory pathways and candidate gene modules.On the technological front,the development of machine learning-driven genomic prediction models and modular breeding platforms has markedly enhanced the accuracy and efficiency of selection for complex traits.Exemplified by the commercial layer strain Jingfen No.6,which has achieved the goal of"500 eggs in 700 days",these advancements signify the transition of extended laying-cycle breeding from theoretical exploration to industrial application.This review aims to provide a systematic theoretical framework and technical reference to support the high-quality and sustainable development of the layer industry.