磷酸化蒲公英多糖对雏鸡生长性能、免疫功能及肠道健康的影响OA

The experiment aimed to investigate the effects of phosphorylated dandelion polysaccharide on the growth performance,immune function,and intestinal health of chicks.A total of 240 Taihang chicks aged one day were randomly divided into four groups,with six replicates per group and 10 chicks per replicate.Groups CON and CY were fed a basal diet,while the groups TP and PTP were fed the basal diet supplemented with 800 mg/kg dandelion polysaccharide and 800 mg/kg phosphorylated dandelion polysaccharide,respectively.Groups CY,TP,and PTP were injected with 80 mg/kg cyclophosphamide on days 4 to 6 to establish the immunosuppressive model.The trial lasted for 42 days.The results showed that on day 42,the average daily gain,average daily feed intake,and serum alanine aminotransferase(ALT)and aspartate aminotransferase(AST)activities in group PTP were significantly higher than those in groups CON and TP(P<0.05),and the spleen and bursa of Fabricius indices in group PTP were significantly higher than those in group TP(P<0.05).The serum concentrations of immunoglobulin G(IgG),immunoglobulin M(IgM),interleukin-2(IL-2),interleukin-6(IL-6),and interleukin-1β(IL-1β)in the group PTP were significantly higher than those in the other groups(P<0.05).The villus height and crypt depth of the duodenum,jejunum,and ileum in the group PTP were significantly higher than those in the other groups(P<0.05),and the concentrations of IgG,secretory immunoglobulin A(sIgA),IL-2,IL-6,IL-1β,and tumor necrosis factor-α(TNF-α)in the jejunal tissue were significantly higher than those in groups CON and TP(P<0.05).The study shows that dietary supplementation with phosphorylated dandelion polysaccharide improves growth performance,enhances immune function,and promotes intestinal health in chicks,and its efficacy is superior to that of dandelion polysaccharide.