基于"形神一体观"探讨肠易激综合征脑肠互动机制及治疗OA

Irritable bowel syndrome(IBS)is a common functional gastrointestinal disorder,the onset of which is closely related to brain-gut interaction and psychological factors.According to"unity of body and spirit"in traditional Chinese medicine(TCM),body is the residence of spirit,and spirit is the master of body,both in an interdependent and mutually influencing relationship.This is in line with the brain-gut axis theory of modern medicine.Consequently,IBS can be categorized as a"comorbidity of body and spirit".Specifically,the disease is located in the intestine;its onset is closely related to the dysfunctions of heart,liver,spleen,kidney,and other zang-fu organs,with disorder of qi movement and emotional disturbance as the core links.Treatment should elaborate"brain-gut co-regulation".The functional balance of the brain-gut axis can be restored by soothing liver and invigorating spleen to regulate the(spleen and stomach)pivot,by nourishing heart and invigorating spleen to tranquilize spirit and enhance transportation,and by warming kidney and invigorating spleen to assist yang and regulate spirit.This study aims to provide a novel idea and a new theoretical basis for TCM treatment of IBS.