儿童期不良经历与老年人抑郁症状的关联OA

Aim:To explore the association between adverse childhood experience(ACE)and depressive symptoms a-mong older adults.Methods:A total of 8 047 older adults aged over 60 years were selected from the China Health and Re-tirement Longitudinal Study(CHARLS).The 10-item Center for Epidemiologic Studies Depression Scale(CESD-10)was applied to evaluate depressive symptoms.Ten types of ACE were extracted from CHARLS,with 1 point awarded for each type of experience.Participants were divided into the high-ACE group(score≥4),low-ACE group(score 1-3)and zero-ACE group(score 0).Univariate analysis and Logistic regression analysis were performed to investigate the association be-tween ACE and depressive symptoms in older adults.Results:After adjusting for confounding factors,compared with the ze-ro-ACE group,the high-ACE group had a higher risk of depressive symptoms[OR(95％CI)=2.158(1.658-2.809)].Older adults with parental depression,parental disability,dangerous growing-up environment,childhood loneliness,childhood hunger and childhood bullying presented a higher risk of depressive symptoms[OR(95％CI)=1.475(1.313-1.656),1.337(1.078-1.658),1.300(1.089-1.551),1.309(1.135-1.509),1.208(1.061-1.374),1.244(1.108-1.397)].Conclusion:A higher number of ACEs,as well as individual ACEs including parental depression,parental disa-bility,dangerous growing-up environment,childhood loneliness,childhood hunger and childhood bullying,may increase the risk of depressive symptoms in older adults.