加味潜阳封髓丹对阳虚火浮证支气管哮喘患者肺功能及炎症因子的影响OA

Objective To investigate the effects of the modified Qianyang Fengsui mini-pill on lung function and inflammatory factors in patients with bronchial asthma presenting with yang deficiency and fire floating syndrome.Methods A total of 120 patients with bronchial asthma of yang deficiency and fire floating syndrome were retrospectively analyzed,who were admitted to Department of Pulmonary Diseases of Chongqing Hospital of the First Affiliated Hospital of Guangzhou University of Chinese Medicine.They were divided into two groups according to the treatment.A total of 54 patients treated with Western medicine alone were included in the control group,and 66 patients treated with the modified Qianyang Fengsui mini-pill combined with Western medicine were included in the experimental group.The therapeutic effects,lung function indicators and inflammatory factor levels before and after treatment were compared between the two groups.Results The total effective rate in the experimental group was higher than that in the control group(P<0.05).After treatment,the forced expiratory volume in one second(FEV1),the percentage of FEV1 to forced vital capacity(FEV1/FVC),and the peak expiratory flow(PEF)in the experimental group all increased compared to pre-treatment levels and were higher than those in the control group,with statistically significant differences(P<0.05).The serum eosinophil count(EOS)and serum interleukin-6(IL-6)levels in the experimental group were both lower than pre-treatment levels and lower than those in the control group,with statistically significant differences(P<0.05).Conclusion Modified Qianyang Fengsui mini-pill in the treatment of bronchial asthma of yang deficiency and fire floating syndrome could improve lung function,suppress airway inflammation,and effectively enhance clinical efficacy.