疏风凉血法治疗慢性肾脏病1-2期慢性肾炎综合征的临床研究OA

Objective To explore the clinical efficacy of wind-dispersing and blood-cooling therapy in the treatment of chronic nephritic syndrome at chronic kidney disease(CKD)Stage 1-2.Methods A total of 60 patients with chronic nephritic syndrome at CKD stage 1-2 admitted to Xinyu Hospital of Traditional Chinese Medicine from February 2024 to February 2025 were enrolled and randomly divided into a control group and an observation group,with 30 cases in each group.The control group received dietary guidance and conventional treatment.On this basis,the observation group was additionally treated with Chinese herbal medicine based on wind-dispersing and blood-cooling therapy.Both groups received treatment for 8 weeks.The traditional Chinese medicine(TCM)syndrome scores,blood pressure,laboratory indicators(serum creatinine,blood urea nitrogen,24-hour urinary protein,urinary red blood cells)and clinical efficacy were observed and recorded before and after treatment in the two groups.Results The laboratory indicators,blood pressure and TCM syndrome scores were decreased in both groups,while the reduction was significantly greater in the observation group(P<0.05).The total effective rate of the observation group was 93.33%,which was higher than 73.33%of the control group(P<0.05).Conclusion Wind-dispersing and blood-cooling therapy could improve patients'clinical symptoms and delay renal function deterioration,and possessed high clinical application value.