冠状动脉CT血流储备分数对PCI术后近期支架内再狭窄预测的增量价值OA

Objective:To investigate the incremental value of coronary CT flow fractional reserve(CT-FFR)in predicting in-stent restenosis(ISR)within 1 year after percutaneous coronary intervention(PCI)in patients with acute myocardial infarction(AMI).Methods:AMI patients admitted to the 980th Hospital of the Chinese People's Liberation Army Joint Logistic Support Force from February 2022 to March 2024 were retrospectively included.Among them,62 patients had ISR within 1 year after operation(ISR group),and 62 patients without ISR(non-ISR group)were matched by 1∶1 ratio.The clinical data of all patients were collected and the CT-FFR values were measured.Multivariate Logistic regression was used to analyze the independent influencing factors of ISR,and the receiver operating characteristic(ROC)curve was used to evaluate the predictive efficacy of the traditional risk factor model and the model combined with CT-FFR on ISR.Results:Multivariate Logistic regression analysis showed that hypertension,diabetes,low-density lipoprotein cholesterol(LDL-C),C-reactive protein(CRP),N-terminal pro-brain natriuretic peptide(NT-proBNP)and mean CT-FFR were independent influencing factors of ISR at 1 year after PCI(P＜0.05).ROC curve analysis showed that the area under the curve(AUC)of the model combined with CT-FFR for predicting ISR was 0.945(95％CI:0.890～0.978),which was significantly higher than that of the model containing only traditional risk factors(P＜0.05).Conclusion:Combining CT-FFR with traditional risk factors can significantly improve the predictive ability of ISR within 1 year after PCI in patients with AMI,and has important incremental predictive value.