基于"一阴为独使"探讨慢性乙型肝炎"炎-癌"转化及防治OA

The"inflammation-cancer"transformation in chronic hepatitis B(CHB)eventually leads to primary liver cancer,and its pathological mechanism is extremely complex."The Suwen"posits that"one yin acts as the sole envoy."Later medical scholars expounded its meaning,stating that Jueyin was the pivot where yin and yang intersected;For those whose yin and yang failed to interact smoothly,regulating the liver should be paramount.The progression of CHB-induced hepatocellular carcinoma aligns with the principles of liver qi disharmony,yin-yang disconnection,and disruption of the ying-wei circulation.Prolonged external pathogenic toxins entrenched in the Jueyin channel obstruct liver collaterals'qi movement,leading to yin deficiency with hyperactivity of yang;The mutual entanglement of phlegm and stasis then creates a pattern of yin excess with suppressed yang;Ultimately,malignant transformation arises internally,culminating in depleted yin and weakened yang.Therefore,it is necessary to early observe the signs of Qi movement stagnation,so as to block the path of transmission and transformation of abdominal mass.This paper takes Yin-Yang as the hub,and explores the evolution of the pathogenesis of"inflammation-cancer"transformation.By integrating the principles of modern medicine and inheriting the essence of holistic regulation in traditional Chinese medicine(TCM),this paper expounds on the practical effects of combining multiple therapies to provide references for the prevention and treatment of CHB and its subsequent complications.