基于"津液涩渗,着而不去"探讨肿瘤高凝状态病机与防治OA

Tumor hypercoagulability represents a pathological state arising from the combined effects of deficiency of vital qi and abnormal body fluid metabolism during tumor progression,which tends to induce severe complications such as thrombosis and embolism.Based on the theory of"body fluids becoming viscous and stagnant,adhering without resolution",it is found that the pathogenesis of tumor hypercoagulability presents a dynamic progression of"qi deficiency → body fluid depletion → obstruction and retention → blood stasis obstruction."Guided by the principles of qi deficiency,yin deficiency,and yang deficiency,it manifests in three progressive stages:(1)Initial stage:Qi deficiency and body fluid depletion,with loss of fluid nourishment as the foundational trigger;(2)Intermediate stage:Dual deficiency of qi and yin,with mutual entanglement of phlegm and stasis as the pivotal progression;(3)Terminal stage:Yang deficiency and cold stagnation,with deep accumulation of stasis toxins as the final outcome.Based on this,a phased prevention and treatment system is established.In the initial stage,it tonifies qi and nourishes yin,promotes body fluid production and dredges meridians;In the intermediate stage,it nourishes yin and dredges collaterals,resolves phlegm and disperses stasis;In the terminal stage,it warms yang and dredges meridians,resolves stasis and detoxifies.By multidimensionally regulating body fluid metabolism and balancing vital qi and pathogenic factors,this system improves the hypercoagulability,aiming to provide insights for TCM clinical prevention and treatment based on syndrome differentiation of tumor hypercoagulability.