从"伏邪外发"病机探析中医防治乳腺癌术后复发机理OA

High recurrence rate and treatment resistance are core dilemmas in clinical diagnosis and treatment of breast cancer.Ren Jixue's theory of"latent pathogen erupting externally"originates from classical theories of traditional Chinese medicine(TCM),and profoundly reveals the pathological evolutionary process of latent pathogenic factors from dormancy and progression to postoperative recurrence of breast cancer.This paper systematically elaborates on the TCM connotation and modern biological characteristics of latent pathogens,and deeply analyzes their molecular correlations between latent pathogens and tumor microenvironment remodeling,invasion and metastasis,as well as therapeutic resistance.This article clarifies the construction of a diagnosis and treatment system featuring syndrome differentiation by stages,simultaneous treatment of root cause and manifestations,and collaboration of traditional Chinese and Western medicine,along with the clinical application of blood stasis-resolving and phlegm-eliminating medicinal herbs,providing novel theoretical basis and practical strategies for the precise prevention and control of tumors and their recurrence.