仝小林"独藏"辨识治疗难治性功能性消化不良OA
Treatment of refractory functional dyspepsia through identification of the only core symptom hidden in many symptoms by Professor Tong Xiaolin
难治性功能性消化不良以餐后饱胀、早饱感、上腹部疼痛或烧灼感为主要表现,症状多不典型,常规西药治疗后易复发,临床辨治棘手."独藏"辨识是仝小林提出的以抓主症为核心,疾病为纲领,辨证为枢纽,由病定域、由症入机、由机立法、由法选方的辨治思路.本案患者除胃脘胀满、早饱,伴胃怕凉、便溏诸症,兼见反复发作的口腔溃疡,表面凹陷,周边红肿,辨识口腔溃疡为本案"独藏症",由溃疡之热与脾胃之寒,直指脾胃虚弱、寒热错杂、气机壅滞之病机,治以补益脾胃、辛开苦降、寒热同调,方用甘草泻心汤加减.对于此类伴反复口腔溃疡的难治性功能性消化不良,可从"独藏症"入手,提高辨治的针对性.
Refractory functional dyspepsia(RFD)is mainly characterized by postprandial fullness,early satiation,and epigastric pain or burning sensation.Due to the atypical nature of its symptoms and the tendency for recurrence after conventional Western medicine treatment,its treatment based on syndrome differentiation is quite challenging.The"Ducang"(the only core symptom hidden in many symptoms)identification is treatment based on syndrome differentiation approach proposed by Professor Tong Xiaolin,which takes grasping the main symptoms as the core,the disease as the guiding principle,syndrome differentiation as the pivot,and follows the steps of determining the disease domain based on the disease,understanding the pathogenesis based on the symptoms,establishing therapeutic methods based on pathogenesis,and selecting formulas according to therapeutic methods.In this case,the patient presented with not only epigastric fullness,early satiation,accompanied by aversion to cold in the epigastrium,loose stools and other symptoms,but also recurrent oral ulcers characterized by depressed ulcer surfaces and surrounding erythema.The oral ulcers were identified as the"Ducang symptom"of this case.In this case,by integrating the heat manifested by the ulcers with the coldness of the spleen and stomach,the underlying pathogenesis was further identified as spleen–stomach deficiency,cold–heat complexity,and stagnation of qi in the middle jiao.In this case,treatment focused on tonifying the spleen and stomach,regulating the middle jiao through the simultaneous use of acrid-warm and bitter-cold herbs,and harmonizing cold and heat,with modified Gancao Xiexin Decoction as the principal formula.For patients with RFD accompanied by recurrent oral ulcers,treatment can start from"Ducang symptom"to enhance the pertinence of treatment based on syndrome differentiation.
米文静;陈科宇;刘源鸿;唐程;仝小林
中国中医科学院广安门医院代谢病研究所,北京 100053青岛大学附属医院中医科,山东 青岛 266003北京中医药大学研究生院,北京 100029北京中医药大学北京中医药研究院,北京 100029中国中医科学院广安门医院代谢病研究所,北京 100053
医药卫生
独藏难治性功能性消化不良口腔溃疡甘草泻心汤中医病案
the only core symptom hidden in many symptomsrefractory functional dyspepsiaoral ulcerGancao Xiexin DecoctionChinese medical case reports
《长春中医药大学学报》 2026 (10)
1135-1138,4
癌症、心脑血管、呼吸和代谢性疾病防治研究国家科技重大专项(2024ZD0523400)
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