膨胀水分离技术在超声引导下乳腺良性肿瘤微创旋切手术中的应用效果及对血清炎性因子的影响OA
Application of expansive water separation technique in ultrasound-guided minimally invasive rotary resection of benign breast tumor and its influences on serum inflammatory factors
目的:分析膨胀水分离技术在超声引导下乳腺良性肿瘤微创旋切手术中的应用效果及对血清炎性因子的影响.方法:选取492例乳腺良性肿瘤患者为研究对象,根据局部麻醉方式的不同分为传统浸润麻醉组(n=234,传统局部浸润麻醉)与膨胀水分离组(n=258,膨胀水分离技术).两组患者均在超声引导下行微创旋切术.对比两组患者围术期相关指标(手术时间、术中出血量、麻醉时间、住院时间)、视觉模拟评分(VAS)、血清白细胞介素6(IL-6)、IL-10、C反应蛋白(CRP)、肿瘤坏死因子α(TNF-α),记录并发症及温哥华瘢痕量表(VSS).结果:与传统浸润麻醉组比较,膨胀水分离组手术时间更短(P<0.05),术中VAS评分更低(P<0.05),麻醉时间更长(P<0.05);术后3 d,膨胀水分离组血清IL-6、IL-10、CRP、TNF-α水平均低于传统浸润麻醉组(P<0.05);膨胀水分离组并发症发生率低于传统浸润麻醉组(P<0.05);术后6个月,膨胀水分离组VSS各维度评分均低于传统浸润麻醉组(P<0.05).结论:膨胀水分离技术应用于超声引导下乳腺良性肿瘤微创旋切手术,可缩短手术时间,减轻术中疼痛,抑制炎性反应,提升乳房美观度,减少并发症.
Objective:To analyze application of expansive water separation technique in ultrasound-guided minimally invasive rotary resection of benign breast tumor and its influences on serum inflammatory factors.Methods:A total of 492 patients with benign breast tumors undergoing ultrasound-guided minimally invasive rotary resection were enrolled.According to different local anesthesia methods,they were divided into traditional infiltration anesthesia group(n=234,traditional local infiltration anesthesia)and expansive water separation group(n=258,expansive water separation technique).The perioperative indexes(operation time,intraoperative blood loss,anesthesia time,length of hospital stay),scores of visual analogue scale(VAS),levels of serum interleukin(IL)-6,IL-10,C-reactive protein(CRP)and tumor necrosis factor-α(TNF-α)were compared between the two groups.The occurrence of complications and score of Vancouver scar scale(VSS)were recorded.Results:Compared with traditional infiltration anesthesia group,operation time was shorter(P<0.05),intraoperative VAS score was lower(P<0.05),and anesthesia time was longer in expansive water separation group(P<0.05).At 3 d after surgery,levels of serum IL-6,IL-10,CRP and TNF-α in expansive water separation group were lower than those in traditional infiltration anesthesia group(P<0.05).The incidence of complications in expansive water separation group was lower than that in traditional infiltration anesthesia group(P<0.05).At 6 months after surgery,VSS scores in expansive water separation group were lower than those in traditional infiltration anesthesia group(P<0.05).Conclusion:The application of expansive water separation technique in ultrasound-guided minimally invasive rotary resection of benign breast tumor can shorten operation time,relieve intraoperative pain,inhibit inflammatory response,improve breast aesthetics and reduce complications.
张磊;李梦新;李爽;蒋宏传
首都医科大学附属北京积水潭医院普外科,北京 100035首都医科大学附属北京朝阳医院乳腺外科,北京 100020首都医科大学附属北京积水潭医院普外科,北京 100035首都医科大学附属北京朝阳医院乳腺外科,北京 100020
医药卫生
膨胀水分离技术超声引导微创旋切手术乳腺良性肿瘤炎性因子
Expansive water separation techniqueUltrasound guidanceMinimally invasive rotary resectionBenign breast tumorInflammatory factor
《川北医学院学报》 2026 (9)
1083-1087,5
北京市科技计划课题(D161100000816002)
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