A型肉毒毒素精准注射技术治疗脑卒中后上肢痉挛的临床疗效OA

Objective:To evaluate the clinical effect of the precise botulinum toxin type A(BoNT-A)injection technique in treating post-stroke upper limb spasticity.Methods:A total of 105 patients with post-stroke upper limb spasticity who visited the First Affiliated Hospital of Guangxi University of Chinese Medicine from March 2023 to March 2024 were selected and randomly divided into control group 1(conventional rehabilitation),control group 2(conventional rehabilitation+freehand BoNT-A injection),and an observation group(conventional rehabilitation+precise BoNT-A injection),with 35 cases in each group.All three groups received continuous treatment for 14 days.The Modified Ashworth Scale(MAS),the Fugl-Meyer Assessment of the Upper Extremity(FMA-UE),and the Activities of Daily Living(ADL)scale were used to assess and compare functional improvements among the three groups before treatment,after treatment,and at the 4-week follow-up,and the overall therapeutic effects of the three groups were compared.Results:The total effective rate was 97.15%in the observation group and 94.28%in control group 2,with no statistically significant difference between the two groups(P>0.05).However,the marked effectiveness rate of the observation group(82.86%)was significantly higher than those of control group 2(48.57%)and control group 1(40.00%)(P<0.05).After 14 days of treatment,all three groups showed significant efficacy after treatment and at the 4-week follow-up.The reduction in MAS scores and the increases in FMA-UE and ADL scores in the observation group were all greater than those in the two control groups,with statistically significant differences(P<0.05).Conclusion:Precise botulinum toxin type A injection can significantly relieve post-stroke upper limb spasticity and enhance motor function and activities of daily living.It is particularly superior to freehand injection in terms of the degree of improvement in spasticity and motor function,and thus has important value for wider clinical application.