从"络脉-膜原-肠腑"论治溃疡性结肠炎发作期OA
Exploration on Treating Active Ulcerative Colitis from the"Collaterals-Moyuan-Intestinal Fu Viscera"Pathway
本文立足中医络病理论与膜原学说,结合溃疡性结肠炎(UC)发作期黏膜溃烂、出血的病理特征,创新提出"络脉-膜原-肠腑"通路为UC发作期"络瘀肠溃"病机的核心传变载体.基于此通路"络瘀为根、膜壅为介、肠溃为果"的递进特征,本文构建"宣通膜原以化瘀、通络散瘀以安肠、敛疮修复以愈溃、健脾固络以防复"的治疗体系,明确核心药对与配伍逻辑,并结合临床验案佐证.
Based on the traditional Chinese medicine(TCM)collateral disease theory and the doctrine of moyu-an,combined with the pathological characteristics of mucosal erosion and hemorrhage in active ulcerative colitis(UC),this paper innovatively proposes that the"collateral-moyuan-intestinal fu viscera"pathway serves as the core transmission carrier of the pathogenesis of intestinal ulceration due to collateral stasis in active UC.Accord-ing to the progressive characteristics of this pathway,namely"collateral stasis as the root,moyuan stagnation as the intermediate link,and intestinal ulceration as the consequence",a therapeutic framework is established:diffus-ing and unblocking moyuan to resolve stasis,dredging collaterals and dissipating stasis to calm intestines,con-straining sores and promoting tissue repair to heal ulceration,invigorating spleen and consolidating collaterals to prevent recurrence.The core herb pairs and compatibility principles are clarified,and relevant clinical cases are presented for verification.
俞姝含;鲁梦捷;李文杰;杨伯霖
南京中医药大学附属医院,江苏省中医院,江苏 南京 210029南京中医药大学附属医院,江苏省中医院,江苏 南京 210029南京中医药大学附属医院,江苏省中医院,江苏 南京 210029南京中医药大学附属医院,江苏省中医院,江苏 南京 210029
医药卫生
溃疡性结肠炎络病理论膜原学说"络脉-膜原-肠腑"通路络瘀肠溃
Ulcerative colitisCollateral disease theoryDoctrine of moyuan"Collateral-moyuan-intestinal fu viscera"pathwayIntestinal ulceration due to collateral stasis
《中国中医急症》 2026 (9)
1046-1050,5
国家自然科学基金项目(82474265)江苏省中医院院级课题(Y25021)
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