重大传染病患者继发医院感染防控路径及评价建议OA

Patients with major infectious diseases are at high risk of secondary hospital-acquired infections due to compromised immune function and the high burden of environmental contamination with hospital-acquired infection pathogens in the admitting departments.These infections are predominantly endogenous or environmentally acquired exogenous infections,are difficult to recognize early,and represent a weak point in hospital-acquired infection prevention and control.Building upon standard hospital-acquired infection prevention and control strategies,this prevention and control pathway proposes systematic enhanced measures targeting the above-mentioned specific risks.This pathway includes protecting patients' own microbiota,safeguarding open body cavities,active screening and decolonization,built environment control,and environmental cleaning and disinfection.It also recommends a closed-loop management system through infection surveillance and review,post-discharge follow-up,and environ-mental sampling.This pathway aims to provide healthcare facilities with a reference framework for targeted preven-tion and control to reduce the incidence of secondary hospital-acquired infections in patients with major infectious diseases and to ensure patient safety.