芪参益气滴丸联合西药治疗对冠心病合并心衰患者心功能及预后的影响OA

Objective To investigate the effects of Qishen Yiqi Dripping Pills combined with Western medicine on cardiac function and prognosis in patients with coronary heart disease(CHD)complicated by heart failure.Methods A total of 76 patients with CHD complicated by heart failure who were admitted to Tongxu First Hospital from October 2023 to January 2026 were randomly divided into two groups using a random number table method,with 38 patients in each group.The control group received guideline-directed standardized Western medical therapy,whereas the observation group received integrated traditional Chinese and Western medicine treatment with the addition of Qishen Yiqi Dripping Pills.Clinical efficacy,cardiac function parameters,serum biomarkers,inflammatory factors,and prognostic outcomes were compared between the two groups.Results The overall response rate was higher in the observation group than in the control group(P＜0.05).After treatment,cardiac output(CO)and left ventricular ejection fraction(LVEF)were higher in the observation group,whereas left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),N-terminal pro-B-type natriuretic peptide(NT-proBNP),homocysteine(Hcy),and inflammatory factor levels were lower than those in the control group(P＜0.05).The incidence of adverse cardiac events,including cardiovascular rehospitalization,arrhythmia,and angina pectoris,was also lower in the observation group(P＜0.05).Conclusion Compared with Western medical therapy alone,the addition of Qishen Yiqi Dripping Pills in patients with CHD complicated by heart failure may improve clinical efficacy and cardiac function,reduce serum Hcy and NT-proBNP levels,attenuate inflammatory responses,and decrease the incidence of adverse cardiac events such as cardiovascular rehospitalization,arrhythmia,and angina pectoris,thereby improving short-term prognosis.