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基于"脾实秽去"理论论治溃疡性结肠炎OA

Treatment of ulcerative colitis based on theory of"fortifying spleen to eliminate turbid filth"

中文摘要英文摘要

基于"脾实秽去"理论探讨溃疡性结肠炎发生发展过程中的病机演变规律及治疗策略.溃疡性结肠炎的病机演变过程可概括为脾虚湿蕴、湿热毒瘀内结,正虚邪恋、伏毒留滞,脾肾精亏、迁延反复,呈现因虚致实、因实致虚、虚实夹杂的特点;提出祛浊邪、泻阴火,以补为通、去秽实脾,补肾精以助脾精、化气去秽,以及局部用药速去浊邪等治疗思路.并附验案1则.

This paper investigates the patterns of pathological progression and explores therapeutic strategies for ulcerative colitis(UC)based on the theory of"fortifying the spleen to eliminate turbid filth".The pathological progression of UC can be generalized into three distinct stages:spleen deficiency with dampness accumulation resulting in the internal binding of damp-heat,toxins,and blood stasis;coexistence of healthy qi deficiency and lingering pathogens characterized by latent toxins;and deficiency of spleen and kidney essence leading to prolonged and recurrent disease.Overall,UC presents a complex feature of deficiency complicating with excess,where deficiency induces excess and vice versa.Therefore,this paper proposes several therapeutic approaches:removing turbid pathogens and purging yin-fire;achieving patency through tonification to eliminate filth and fortify the spleen;nourishing kidney essence to supplement spleen essence and promoting qi transformation to clear filth;and applying localized medication to rapidly eliminate turbid pathogens.A representative case is presented for illustration.

李沛鸿;陈安斌;胡鸿毅

上海中医药大学附属龙华医院脾胃科(上海 200032)上海中医药大学附属龙华医院脾胃科(上海 200032)上海中医药大学附属龙华医院脾胃科(上海 200032)

溃疡性结肠炎脾实秽去阴火去腐生新中医药疗法

ulcerative colitisfortifying the spleen and eliminating turbid filthyin-fireremoving necrotic tissues and promoting regenerationtraditional Chinese medicine therapy

《上海中医药杂志》 2026 (10)

39-45,7

国家自然科学基金项目(82074366)中国中医科学院"中国中医药联合研究生院"科教专项课题(CI2023C020LH)

10.16305/j.1007-1334.2026.z20260116004

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