个体化营养干预在老年胰岛素抵抗并发肌少症中的应用效果OA
Application effect of individualized nutritional intervention in elderly pa-tients with insulin resistance complicated with sarcopenia
目的 探讨个体化营养干预在老年胰岛素抵抗并发肌少症患者中的应用效果.方法 选取2023年1月至2025年8月锦溪人民医院收治的82例老年胰岛素抵抗并发肌少症患者作为研究对象,按照随机数字表法分为治疗组和对照组,每组41例.对照组给予常规营养指导,治疗组实施个体化营养干预,持续干预12周.比较两组干预前后肢体功能指标(握力、四肢骨骼肌量指数、简易体能状况量表评分)、血糖调控指标(空腹血糖、糖化血红蛋白、胰岛素抵抗指数)及营养状态指标(白蛋白、前白蛋白),记录不良反应发生情况.结果 干预后,治疗组握力、四肢骨骼肌量指数、简易体能状况量表评分高于对照组,差异有统计学意义(P＜0.05).治疗组空腹血糖、糖化血红蛋白、胰岛素抵抗低于对照组,差异有统计学意义(P＜0.05).治疗组白蛋白、前白蛋白均高于对照组,差异有统计学意义(P＜0.05).治疗组不良反应总发生率低于对照组,差异有统计学意义(P＜0.05).结论 个体化营养干预可有效改善老年胰岛素抵抗并发肌少症患者的肢体功能,优化血糖调控效果,提升营养状态,且安全性良好.
Objective To explore the application effect of individualized nutritional intervention in elderly patients with in-sulin resistance complicated with sarcopenia.Methods A total of 82 elderly patients with insulin resistance complicated with sarcopenia who were admitted to Jinxi People's Hospital from January 2023 to August 2025 were selected as the re-search subjects.They were divided into the treatment group and the control group according to the random number table method,with 41 cases in each group.The control group received routine nutritional guidance,while the treatment group implemented individualized nutritional intervention for 12 weeks.The limb function indicators(grip strength,skeletal muscle mass index of the limbs,score of the short physical performance battery),blood glucose regulation indicators(fasting blood glucose,glycosylated hemoglobin,insulin resistance index),and nutritional status indicators(albumin,prealbumin)before and after the intervention were compared between the two groups.The occurrence of adverse reactions was recorded.Results After the intervention,the grip strength,the index of skeletal muscle mass in the limbs,and the score of the simple physical function assessment scale in the treatment group were higher than those in the control group,and the differences were statistically significant(P＜0.05).The fasting blood glucose,glycosylated hemoglobin,and insulin resistance in the treatment group were lower than those in the control group,and the differences were statistically significant(P＜0.05).The albumin and prealbumin levels in the treatment group were higher than those in the control group,and the differences were statistically significant(P＜0.05).The total incidence of adverse reactions in the treatment group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion Individualized nutritional intervention can effectively improve the limb function of elderly patients with insulin resistance complicated with sarcopenia,optimize the effect of blood sugar regulation,enhance the nutritional status,and has good safety.
周军;俞晓琪;王正福
江苏省昆山市锦溪人民医院老年科,江苏昆山 215300江苏省昆山市锦溪人民医院老年科,江苏昆山 215300江苏省昆山市锦溪人民医院老年科,江苏昆山 215300
医药卫生
老年患者胰岛素抵抗肌少症个体化营养干预肢体功能血糖调控
Elderly patientsInsulin resistanceSar-copeniaIndividualized nutrition interventionPhysical functionBlood glucose regulation
《中国当代医药》 2026 (24)
33-36,41,5
江苏省老年医学学会科研课题(JGS2025ZDM004).
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