龙七胃康片治疗慢性胃炎的效果及对胃肠激素、炎症指标的影响OA

Objective To explore the efficacy of Longqi Weikang Tablets in treating chronic gastritis.Methods A total of 88 patients with chronic gastritis admitted to the Department of Gastroenterology of Chengdu Integrated TCM&Western Medicine Hospital from April to December 2024 were selected as the research subjects,they were divided into the control group and the observation group according to random number table method,with 44 cases in each group.The control group was treated with conventional quadruple therapy,while the observation group was treated with quadruple therapy combined with Longqi Weikang Tablets.The Chinese syndrome scores,gastrointestinal hormones(motilin[MOT],pepsinogen Ⅰ[PG Ⅰ],gastrin[GAS]),inflammatory indicators(epidermal growth factor[EGF],interleukin-32[IL-32],transforming growth factor-β1(TGF-β1),nitric oxide[NO]),therapeutic effect and adverse reactions were compared between the two groups.Results After treatment,the Chinese syndrome scores of the observation group were lower than those of the control group,while the levels of MOT,PG Ⅰ and GAS were higher than those of the control group,and the levels of EGF,IL-32 and TGF-β1 were lower than those of the control group,NO was higher than that of the control group,the differences were statisti-cally significant(P＜0.05).The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion For patients with chronic gastritis,treatment with Longqi Weikang Tablets can effectively alleviate symptoms such as epigastric pain and acid reflux,reduce inflammatory responses,increase gastrointestinal hormones levels.The therapeutic effect is remarkable,and have high safety.It is worthy of clinical reference.