住院精神分裂症患者便秘的中医证型及相关因素分析OA

Objective To investigate the traditional Chinese medicine syndrome types and related factors of constipation in hospitalized schizophrenia patients,providing a basis for targeted traditional Chinese medicine clinical treatment.Methods A convenience sampling method was used to select 196 patients with schizophrenia accompanied by constipation who were hospitalized at Shanghai Jiading District Mental Health Center from January to June 2024 as the study subjects.They were divided into deficiency-type constipation(n=140)and excess-type constipation(n=56)according to traditional Chinese medicine syndrome differentiation.Univariate analysis and binary logistic regression analysis were used to examine the differences in demographic,clinical,and emotional factors between the two syndrome-type groups.Results Among the 196 patients with constipation,the deficiency syndrome type accounted for the highest proportion,constituting 71.43％(140/196),and was the predominant syndrome type of constipation.Univariate analysis revealed statistically significant differences between the deficiency and excess syndrome types in terms of daily water intake,Hamilton anxiety scale(HAMA)score,Hamilton depression scale(HAMD)score,sex,marital status,length of hospital stay,and smoking history(P＜0.05).Multivariate analysis showed that HAMA score(β=-0.226,OR=0.798,95％CI:0.682-0.913),male sex(β=1.806,OR=6.084,95％CI:1.550-28.246),divorce(β=2.409,OR=11.125,95％CI:1.341-131.195),and length of hospital stay ≥ 3 years(β=1.628,OR=5.095,95％CI:1.728-17.096)were independent factors influencing the traditional Chinese medicine syndrome types of constipation in hospitalized patients with schizophrenia(P＜0.05).Conclusion The incidence of deficiency constipation syndrome in hospitalized schizophrenia patients is relatively higher among females,those with longer hospital stays,those with higher HAMA scores.Among these,daily water intake can serve as one of the clinical manifestations to help distinguish between excess and deficiency constipation.Medical staff should understand the classification status and influencing factors of constipation in schizophrenia patients,apply syndrome differentiation for treatment and nursing,thereby providing personalized treatment measures for patients.