蒙药治疗急慢性咽炎的研究进展OA
Research progress of Mongolian medicine in treating acute and chronic pharyngitis
咽炎是临床常见的反复发作性疾病,治疗难度较大.蒙药作为我国传统医药的重要组成部分,在急慢性咽炎的治疗中积累了丰富经验,具备疗效确切、不良反应少等特点.本文系统梳理了蒙药治疗急慢性咽炎的相关进展:内服方剂如清咽六味散、玉簪清咽十五味丸等,可发挥抗炎、镇痛、改善咽部症状的作用;放血疗法、熏蒸雾化等外治法也具有一定疗效;单味药中,玉簪、诃子、沙棘、丁香等的活性成分可通过调控核因子κB(NF-κB)、丝裂原活化蛋白激酶(MAPKs)等炎症信号通路发挥治疗作用.目前该领域研究仍存在临床证据等级低、作用机制阐释不深、药效物质基础不清、质量控制标准不统一等问题,未来需通过多中心随机对照试验提升证据等级,深入揭示蒙药复方多靶点抗炎机制,并建立基于活性成分的质控标准,推动蒙药治疗咽炎的循证化与现代化发展.
Pharyngitis is a common recurrent disease in clinical practice,and its treatment is quite challenging.Mongolian medicine,as an important part of traditional Chinese medicine,has accumulated rich experience in the treatment of acute and chronic pharyngitis and possesses the characteristics of definite efficacy and few adverse reactions.This paper systematically reviews the relevant progress of Mongolian medicine in the treatment of acute and chronic pharyngitis:oral medications such as Qingyan Liuwei Powder and Yuzan Qingyan Shiwuwei Pill can exert anti-inflammatory,analgesic,and symptomatic improvement effects;external treatment methods such as bloodletting therapy and fumigation and nebulization also have certain efficacy;among single herbs,the active components of Hosta plantaginea(Lam.)Aschers,Terminalia chebula Retz,Hippophae rhamnoides L,Syringa oblata Lindl,etc can exert therapeutic effects by regulating inflamma-tory signaling pathways such as nuclear factor κB(NF-κB)and mitogen-activated protein kinases(MAPKs).Currently,there are still problems in this field,such as low clinical evidence level,insufficient elucidation of the mechanism of action,unclear pharmacological basis of efficacy,and inconsistent quality control standards.In the future,multi-center randomized controlled trials are needed to improve the evidence level,deeply reveal the multi-target anti-inflammatory mechanism of Mongolian medicine compound,and establish quality control standards based on active ingredients,to promote the evidence-based and modernization development of Mongolian medicine in the treatment of pharyngitis.
刘阳;付卓
内蒙古民族大学基础医学院,内蒙古通辽 028000内蒙古民族大学基础医学院,内蒙古通辽 028000
医药卫生
蒙药咽炎临床治疗综述
Mongolian medicinePharyngitisClinical treatmentReview
《中国当代医药》 2026 (24)
194-198,封3,6
内蒙古自治区一流学科科研专项项目(YLXKZX-NMD-008),内蒙古自治区自然科学基金项目(2025QN08083)内蒙古自治区本级引进人才科研支持项目(RCQD202402)内蒙古民族大学科研启动基金(KYQD23014).
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