六字诀功法训练联合重复经颅磁刺激对痉挛型脑卒中后构音障碍的影响OA
Efficacy of Liuzijue Qigong Exercise Combined with Repetitive Transcranial Magnetic Stimulation on Spastic Post-Stroke Dysarthria
目的 观察六字诀功法训练联合重复经颅磁刺激(rTMS)对痉挛型脑卒中后构音障碍(PSD)的影响.方法 选择2024年9月—2025年9月宜宾市第一人民医院康复医学科收治的痉挛型PSD患者80例,采用随机数字表法分为对照组和观察组,每组40例.研究过程中脱落3例,最终纳入对照组39例、观察组38例.2组均接受常规治疗,对照组在常规治疗基础上,采用高频rTMS刺激左侧大脑半球Broca区、低频rTMS刺激右侧大脑半球Broca镜像区;观察组在对照组基础上联合六字诀功法训练.2组均连续治疗8周.分别于治疗前后采用改良Frenchay构音障碍评价量表(m-FDA)评估患者构音障碍程度,采用言语清晰度(SI)评估工具评估患者言语清晰度,采用嗓音障碍指数(VHI-10)评估患者嗓音情况,采用交流有效性指数(CETI)评估患者交流能力,采用语音学分析软件和分贝仪检测患者声学参数和语言响度,采用中文版脑卒中失语症生活质量量表(SAQOL)评估患者生活质量,采用焦虑自评量表(SAS)和抑郁自评量表(SDS)评估患者心理健康状况.结果 ① m-FDA评分:与治疗前比较,治疗后2组m-FDA各维度评分及总分均明显降低(P<0.05).与对照组比较,观察组治疗后m-FDA反射功能、呼吸功能、颌位置、舌、言语功能评分及总分均较低(P<0.05).② SI、VHI-10和CETI评分:与治疗前比较,治疗后2组SI和CETI评分均明显升高(P<0.05),VHI-10评分明显降低(P<0.05).与对照组比较,观察组治疗后SI和CETI评分均较高(P<0.05),VHI-10评分较低(P<0.05).③ 声学参数:与治疗前比较,治疗后2组第2共振峰(F2)、元音清晰指数(VAI)、最长发声时间(MPT)、最大数数能力(MCA)和语言响度均明显升高(P<0.05),第1共振峰(F1)和共振峰集中率(FCR)均明显降低(P<0.05).与对照组比较,观察组治疗后F2、VAI、MPT、MCA和语言响度均较高(P<0.05),F1和FCR均较低(P<0.05).④ SAQOL、SAS和SDS评分:与治疗前比较,治疗后2组SAQOL评分明显升高(P<0.05),SAS和SDS评分均明显降低(P<0.05).与对照组比较,观察组治疗后SAQOL较高(P<0.05),SAS和SDS评分均较低(P<0.05).结论 六字诀功法训练联合高、低频rTMS可有效改善痉挛型PSD患者构音障碍程度,提高言语清晰度,提升生活质量和心理健康水平.
Objective To observe the efficacy of Liuzijue Qigong exercise combined with repetitive transcranial magnetic stimulation(rTMS)on spastic post-stroke dysarthria(PSD).Methods A total of 80 patients diagnosed with spastic PSD admitted to the Department of Rehabilitation Medicine,the First People's Hospital of Yibin,from September 2024 to September 2025 were recruited and randomly divided into a control group and an observation group using a random number table method,with 40 cases in each group.During the study,3 cases dropped out,resulting in 39 cases in the control group and 38 cases in the observation group.Both groups received conventional treatment.The control group additionally received high-frequency rTMS over the left Broca's area and low-frequency rTMS over the right Broca's mirror area,while the observation group received the identical rTMS protocol combined with Liuzijue Qigong exercise.Both groups were treated continuously for 8 weeks.Before and after treatment,the modi‐fied Frenchay Dysarthria Assessment Scale(m-FDA)was used to assess the severity of dysarthria;the speech intelligibility(SI)assessment was used to assess speech clarity;the Voice Handicap Index-10(VHI-10)was used to assess voice function;the Commu‐nication Effectiveness Index(CETI)was used to assess communication ability;phonetic analysis software and a decibel meter were used to assess acoustic parameters and speech loudness;the Chinese version of Stroke and Aphasia Quality of Life Scale(SAQOL)was used to evaluate quality of life;and the Self-rating Anxiety Scale(SAS)and Self-rating Depression Scale(SDS)were used to assess mental health status.Results(1)m-FDA scores:compared with those before treatment,all m-FDA dimension scores and total scores in both groups decreased significantly after treatment(P<0.05).Compared with the control group,subscores of reflex function,respiratory function,jaw position,tongue function and speech function,and total m-FDA scores in the observation group were lower after treatment(P<0.05).(2)SI,VHI-10,and CETI scores:compared with those before treatment,SI and CETI scores in both groups increased significantly after treatment(P<0.05),while VHI-10 scores decreased significantly(P<0.05).Compared with the control group,SI and CETI scores in the observation group were higher after treatment(P<0.05),and VHI-10 scores was lower(P<0.05).(3)Acoustic parameters:compared with those before treatment,second formant(F2),vowel articulation index(VAI),maxi‐mum phonation time(MPT),maximum counting ability(MCA),and speech loudness in both groups increased significantly after treatment(P<0.05),while first formant(F1)and formant centralization ratio(FCR)decreased significantly(P<0.05).Compared with the control group,F2,VAI,MPT,MCA,and speech loudness in the observation group were higher after treatment(P<0.05),while F1 and FCR were lower(P<0.05).(4)SAQOL,SAS and SDS scores:compared with those before treatment,SAQOL scores in both groups increased significantly after treatment(P<0.05),while SAS and SDS scores decreased significantly(P<0.05).Compared with the control group,SAQOL scores in the observation group was higher after treatment(P<0.05),while SAS and SDS scores were lower(P<0.05).Conclusion Liuzijue Qigong exercise combined with high-frequency and low-frequency rTMS can effectively reduce the severity of dysarthria,enhance speech clarity,and improve quality of life and mental health status in patients with spastic PSD.
余秀芳;吕鑫;付高勇;冯颖;骆立虎;吴燕平;王剑雄
西南医科大学附属医院,四川 泸州 646000||宜宾市第一人民医院,四川 宜宾 644000宜宾市第一人民医院,四川 宜宾 644000宜宾市第一人民医院,四川 宜宾 644000宜宾市第一人民医院,四川 宜宾 644000宜宾市第一人民医院,四川 宜宾 644000宜宾市第一人民医院,四川 宜宾 644000西南医科大学附属医院,四川 泸州 646000||四川省肿瘤医院·研究所,四川 成都 610042
脑卒中构音障碍六字诀功法重复经颅磁刺激高频低频
strokedysarthriaLiuzijue Qigongrepetitive transcranial magnetic stimulationhigh frequencylow frequency
《康复学报》 2026 (9)
631-638,8
四川省卫生健康委员会科技项目(24YWYL05)宜宾市第一人民医院院级研究项目(2024-KYY-27)
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