LigaSure痔切除术联合消痔灵硬化剂注射术治疗混合痔的临床疗效观察OA
Clinical efficacy of LigaSure hemorrhoidectomy combined with Xiaozhiling sclerotherapy for mixed hemorrhoids
目的 观察LigaSure痔切除术联合消痔灵硬化剂注射术治疗混合痔的临床疗效.方法 采用前瞻性随机对照设计,纳入2024年9月至2025年5月在上海市嘉定区中医医院接受手术治疗的110例混合痔患者,采用随机数字表法分为观察组(采用Li-gaSure痔切除术联合消痔灵硬化剂注射术治疗,n=55)和对照组[采用外剥内扎术(Milligan-Morgan术)治疗,n=55].比较两组临床疗效、手术相关指标(创面愈合时间、住院时间、住院费用)及术后并发症(肛门疼痛、肛门出血、肛缘水肿)评分.结果 两组临床总有效率分别为100%和94.5%,比较差异无统计学意义(P>0.05).观察组创面愈合时间、住院时间短于对照组,差异有统计学意义(P<0.05);两组住院费用比较差异无统计学意义(P>0.05).观察组术后肛门疼痛、肛门出血、肛缘水肿评分低于对照组,差异有统计学意义(P<0.05),且观察组术后肛门疼痛、肛缘水肿的改善程度和速率优于对照组.随着时间推移,两组肛门疼痛、肛门出血、肛缘水肿评分呈先升高后降低的趋势(P<0.05).结论 LigaSure痔切除术联合消痔灵硬化剂注射术治疗混合痔的临床疗效与Milligan-Morgan术相当,且能够缩短创面愈合时间及住院时间,减轻术后肛门疼痛、肛门出血及肛缘水肿,不增加住院费用,为肛肠外科治疗混合痔提供了方法参考.
Objectives To investigate the clinical efficacy of LigaSure hemorrhoidectomy combined with Xiaozhiling sclerotherapy in the treatment of mixed hemorrhoids.Methods In this prospective randomized controlled trial,110 patients with mixed hemorrhoids who underwent surgical treatment at Shanghai Jiading District Hospital of Traditional Chinese Medicine between September 2024 and May 2025 were enrolled and randomly assigned to an observation group(treated with LigaSure hemorrhoidectomy combined with Xiaozhiling sclerotherapy,n=55)and a control group(treated with Milligan Morgan hemorrhoidectomy,n=55)using a random number table method.prospective randomized controlled trial was conducted.The two groups were compared in terms of clinical efficacy,surgery-related indicators(wound healing time,hospital stay,hos-pitalization costs),and postoperative complication(anal pain,anal bleeding,perianal edema)scores.Results The total clinical effective rates were 100%in the observation group and 94.5%in the control group,with no statistically significant difference(P>0.05).The observation group had significantly shorter wound healing time and hospital stay than the control group(P<0.05),while no significant difference was found in hospitalization costs between the two groups(P>0.05).The observation group also had significantly lower postoperative scores for anal pain,anal bleeding,and perianal edema compared with the control group(P<0.05),and demonstrated better improvement and faster resolution of anal pain and perianal edema over time.In both groups,scores for anal pain,pain bleeding,and perianal edema initially increased and then decreased over time(P<0.05).Conclusions LigaSure hemorrhoidectomy combined with Xiaozhiling sclerotherapy achieves clinical efficacy comparable to Milligan-Morgan hemorrhoidectomy for mixed hemorrhoids,while offering advantages of shorter wound healing time,reduced hospital stay,and less postoperative anal pain,anal bleeding,and perianal edema without increasing hospitalization costs.This combined approach provides a valuable reference for the surgical management of mixed hemorrhoids in anorectal practice.
张辉;高洪娣;张金华;朱亚萍
上海市嘉定区中医医院肛肠科 上海 201800上海市嘉定区中医医院肛肠科 上海 201800上海市嘉定区中医医院肛肠科 上海 201800上海市嘉定区中医医院肛肠科 上海 201800
医药卫生
混合痔LigaSure痔切除术消痔灵硬化剂注射术外剥内扎术
mixed hemorrhoidsLigaSure hemorrhoidectomyXiaozhiling sclerotherapyMilligan-Morgan hemorrhoidectomy
《结直肠肛门外科》 2026 (4)
386-390,5
上海市嘉定区卫生健康委员会科研课题计划(2023-KY-07)
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