基于"乙癸同源"理论论治早发性卵巢功能不全的思路探析OA

Premature ovarian insufficiency(POI)is a common reproductive endocrine disorder in gynecology,yet modern medical treatments for the condition remain limited.The Traditional Chinese Medicine(TCM)theory of"Yikui Tongyuan"(referring to the Liver and Kidney)elucidates the close relationship between these two organs:physiologi-cally,they share a mutual transformation of essence and blood and jointly govern reproductive functions;pathologically,they mutually influence one another.The author systematically explores the intrinsic link between POI and this theory,positing that the primary pathogenesis involves a deficiency of Liver and Kidney essence and blood,alongside the pre-mature exhaustion of"Tiangui".A therapeutic approach is proposed that prioritizes"nourishing water to nurture wood"and"replenishing essence to nourish blood",while simultaneously"regulating Qi and blood"and"calming the heart and spirit".This approach emphasizes dynamic syndrome differentiation aligned with the menstrual cycle,and a veri-fied clinical case is presented to substantiate these concepts.This study offers a clinical framework for treating POI by targeting the Liver and Kidney,demonstrating the advantages of the holistic view and syndrome differentiation charac-teristic of TCM.