465例"肝经-腺体病"横断面调查研究OA

Objective:Grounded in meridian theory and clinical practice,our research team proposes the"liver meridian-glandular disease"hypothesis.This study aims to clarify the fundamental clinical characteristics of"liver meridian-glandular disease"and explore its underlying mechanisms by investigating glandular diseases within the distribution region of the liver meridian.Methods:A cross-sectional survey was conducted to document glandular disorders in the liver meridian distribution area among individuals undergoing physical examinations at the Health Check-up Center of Jiangsu Provincial Hospital of Chinese Medicine.Descriptive statistics and correlation analyses were performed on the collected data using SPSS 26.0 software.Results:A total of 541 participants were enrolled,among whom 465(85.95％)presented with glandular diseases in the liver meridian distribution area.Specifically,219 cases(47.10％)had single gland disease,and 246 cases(52.90％)had polyglandular diseases.In female participants,thyroid diseases were the most prevalent(67.29％),whereas liver(gallbladder)diseases predominated in male participants(86.45％).For females with"liver meridian-glandular diseases",correlations were observed between thyroid and breast diseases,as well as between ovarian(uterine)and liver(gallbladder)diseases.In males,correlations were identified between thyroid and prostate diseases,and between thyroid and liver(gallbladder)diseases.Conclusion:The proposal of the"liver meridian-glandular diseases"hypothesis is supported by both theoretical and clinical evidence.Glandular diseases in the liver meridian distribution area exhibit a"double-high"phenomenon(high overall prevalence and polyglandular diseases prevalence),with significant gender differences in"liver meridian-glandular diseases".From the perspective of modern medicine,this may be associated with the direct or indirect involvement of the liver meridian of Foot-Jueyin in neuro-immune anti-inflammatory processes,endocrine metabolism,and related pathways.