中药阴起石的多技术协同表征与真伪鉴别OA

Objective:To establish a multi-technique collaborative characterization system to analyze the chemical composition and structural characteristics of the mineral medicine Yinqishi,so as to provide a scientific basis for its authenticity identification and quality control.Methods:Combining original research and verification,scanning electron microscopy-energy dispersive spectroscopy(SEM-EDS),Fourier transform infrared spectroscopy(FTIR),and Raman spectroscopy techniques,a systematic analysis was conducted on 32 batches of Yinqishi samples.Results:Bluish-white Yinqishi and cyanish-green Yinqishi samples,preliminarily classified based on their characteristics,exhibited high consistency in elemental composition(Si,Mg,and O totaling over 80%with coordinated distribution),in-frared spectroscopy,and Raman spectroscopy features.By integrating 30 batches of data from both,the infrared fingerprint spectrum(in-cluding 11 characteristic peaks)and Raman fingerprint spectrum(including 12 characteristic peaks)of genuine Yinqishi were success-fully constructed.The similarity coefficients r between the infrared and Raman spectra of all genuine samples and their fingerprint spec-tra were high(infrared r≥0.886,Raman r≥0.964).In contrast,brownish-yellow Yinqishi samples exhibited considerable differences:extremely low Si content and abnormally high Ca content.Their infrared spectra(r=0.674,0.644)and Raman spectra(r=0.911,0.900)both significantly deviated from the genuine fingerprint spectra.Conclusion:This study successfully establishes a"microscopic morphology-elemental composition-functional group-lattice vibration"synergistic characterization system,which can accurately distin-guish the authenticity of Yinqishi and provides innovative and reliable analytical basis for the quality control of mineral medicines.