认知行为疗法联合帕罗西汀对持续性姿势-知觉性头晕患者负性情绪及认知功能的影响分析OA
Analysis of the effects of cognitive behavioral therapy combined with paroxetine on negative emotions and cognitive function in patients with persistent postural-perceptual dizziness
目的 分析认知行为疗法(cognitive behavioral therapy,CBT)联合帕罗西汀对持续性姿势-知觉性头晕(persistent posture-perceptual dizziness,PPPD)患者负性情绪及认知功能的影响.方法 选取2024年1月至2025年12月淮北市人民医院收治的PPPD患者60例作为研究对象,采用随机数字表法分为对照组(n=30)和干预组(n=30).对照组患者行帕罗西汀治疗,干预组患者在对照组治疗基础上接受CBT,干预时间为8周.通过两组干预前后头晕残障问卷量表(dizziness handicap inventory,DHI)、汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)、汉密尔顿抑郁量表(Hamilton depression scale,HAMD)、简明心理状况测验(mini-mental state examination,MMSE)、蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)比较两组患者的临床疗效.结果 最终对照组26例、干预组25例完成研究.经过8周治疗后,干预组患者的DHI各因子及总分、HAMA总分、HAMD总分低于对照组(P<0.05),干预组患者的MMSE总分、MOCA总分高于对照组(P<0.05).结论 CBT联合帕罗西汀可改善PPPD患者的负性情绪及认知功能,以此提高临床治疗的成效,可降低疾病对患者的不利影响.
Objective To analyze the effects of cognitive behavioral therapy(CBT)combined with paroxetine on negative emotions and cognitive functions in patients with persistent postural-perceptual dizziness(PPPD).Methods A total of 60 patients with PPPD from Huaibei People's Hospital from January 2024 to December 2025 were enrolled and randomly assigned to either control group(n=30)or intervention group(n=30)using a random number table.The control group received paroxetine treatment,while the intervention group additionally underwent CBT for a duration of 8 weeks.Clinical efficacy was compared between two groups based on scores obtained from the dizziness handicap inventory(DHI),Hamilton anxiety scale(HAMA),Hamilton depression scale(HAMD),mini-mental state examination(MMSE),and Montreal cognitive assessment(MoCA).Results A total of 26 cases in control group and 25 cases in intervention group completed the study.After 8 weeks of treatment,all components and total scores of the DHI scale,as well as total scores of HAMA and HAMD were lower in intervention group compared to control group(P<0.05).MMSE and MoCA scales were higher in intervention group than those in control group(P<0.05).Conclusion The combination of CBT with paroxetine can improve negative emotions and cognitive function in patients with PPPD,thereby enhancing clinical treatment efficacy and reducing the adverse effects of the disorder on patients.
张玄;张全刚;张嫚茹
淮北市人民医院精神科,安徽 淮北 235000淮北市人民医院精神科,安徽 淮北 235000南京医科大学附属老年医院临床心理科,江苏 南京 210024
医药卫生
认知行为疗法持续性姿势-知觉性头晕负性情绪认知功能
Cognitive behavioral therapyPersistent postural-perceptual dizzinessNegative emotionsCognitive function
《中国现代医生》 2026 (23)
14-18,5
安徽省淮北市科技计划项目(2023HK032)
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