中西医结合分期论治肉芽肿性小叶性乳腺炎的临床效果及生活质量综合评价OA
Comprehensive evaluation of clinical effect and quality of life of integrated traditional Chinese and western medicine in staging therapy of granulomatous lobular mastitis
目的 探讨中西医结合分期论治策略对肉芽肿性小叶性乳腺炎(granulomatous lobular mastitis,GLM)不同阶段的临床疗效及对患者生活质量的改善作用.方法 回顾性分析2022年6月至2024年6月晋江市医院收治的78例GLM患者,将其分为试验组(40例)与对照组(38例).试验组根据分型分期采用中药联合小剂量激素和/或手术治疗,对照组以激素和/或手术治疗为主.比较两组患者的总有效率、复发率、激素使用时长、术后乳房外形满意度和健康调查量表36(36-item short form health survey,SF-36)评分.结果 两组患者的半年治愈率、半年总有效率、1年总有效率比较差异均无统计学意义(P>0.05);试验组患者的1年治愈率显著高于对照组(P<0.05).试验组患者的半年复发率显著低于对照组(P<0.05).试验组患者的激素使用时长显著短于对照组(P<0.05).未接受手术的患者中,试验组患者的乳房外形满意度评分显著高于对照组(P<0.05).治疗后,试验组患者的SF-36总分及心理健康维度评分均显著高于对照组(P<0.05),且SF-36总分与激素使用时长呈负相关、与乳房外形满意度呈正相关(P<0.01).结论 中西医结合分期论治通过降低复发率、减少激素依赖性和改善生活质量,可显著提升GLM的治疗效果,SF-36在综合疗效评估中具有重要价值.
Objective To explore the clinical efficacy of integrated traditional Chinese and western medicine staged treatment strategy in different stages of granulomatous lobular mastitis(GLM)and its effect on improving the quality of life of patients.Methods A retrospective analysis was conducted on 78 patients with GLM who were admitted to Jinjiang Municipal Hospital from June 2022 to June 2024.These patients were divided into experimental group(40 cases)and control group(38 cases).The experimental group was treated with traditional Chinese medicine combined with low-dose hormones and/or surgery according to the classification and stage,while the control group was mainly treated with hormones and/or surgery.The total effective rate,recurrence rate,duration of hormone use,satisfaction with postoperative breast appearance,and the 36-item short form health survey(SF-36)of two groups of patients were compared.Results There was no statistically significant difference in the half-year cure rate,half-year total effective rate,and one-year total effective rate between two groups(P>0.05).The one-year cure rate of experimental group was significantly higher than that of control group(P<0.05).The recurrence rate of patients in experimental group was significantly lower than that in control group within six months(P<0.05).The duration of hormone use for patients in experimental group was significantly shorter than that in control group(P<0.05).Among the patients who did not undergo surgery,the satisfaction score for breast appearance in experimental group was significantly higher than that in control group(P<0.05).After treatment,the total scores of SF-36 and the scores of the mental health dimension in experimental group were significantly higher than those in control group(P<0.05).Moreover,the total score of SF-36 was negatively correlated with the duration of hormone use and positively correlated with the satisfaction with breast appearance(P<0.01).Conclusion The integrated traditional Chinese and western medicine based on stages can significantly enhance the therapeutic effect of GLM by reducing the recurrence rate,decreasing hormone dependence,and improving the quality of life.The SF-36 scale holds significant value in the comprehensive evaluation of therapeutic efficacy.
王卿炜;沈君怡;洪天姿;吴志平;叶泽毅;杨长安;刘婷婷
晋江市医院(上海市第六人民医院福建医院)甲状腺乳腺外科,福建晋江 362200晋江市医院(上海市第六人民医院福建医院)医学影像科,福建晋江 362200晋江市医院(上海市第六人民医院福建医院)甲状腺乳腺外科,福建晋江 362200晋江市医院(上海市第六人民医院福建医院)中医科,福建晋江 362200晋江市医院(上海市第六人民医院福建医院)甲状腺乳腺外科,福建晋江 362200晋江市医院(上海市第六人民医院福建医院)甲状腺乳腺外科,福建晋江 362200晋江市医院(上海市第六人民医院福建医院)甲状腺乳腺外科,福建晋江 362200
医药卫生
肉芽肿性小叶性乳腺炎中西医结合治疗分期论治生活质量
Granulomatous lobular mastitisIntegrated traditional Chinese and western medicineStaging therapyQuality of life
《中国现代医生》 2026 (22)
29-33,5
福建中医药大学校管科研课题(XB2022146)
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