临床药师药学科普干预对缺血性脑卒中患者二级预防的效果评价OA
Evaluation of the effect of clinical pharmacist's pharmaceutical science popularization intervention on secondary prevention for patients with ischemic stroke
目的 评估临床药师实施药学科普干预对缺血性脑卒中患者二级预防的临床价值.方法 选取2024年2月至2025年4月入住清远市人民医院的急性缺血性脑卒中患者222例为研究对象,随机分为对照组(118例)和干预组(104例).对照组给予常规医护健康教育,干预组在此基础之上接受由临床药师提供的系统药学科普干预.比较两组患者出院后1个月和6个月的用药依从性、脑卒中复发率、改良Rankin量表评分及药品不良反应发生率.结果 出院后1个月和6个月时,干预组患者的用药依从性均显著优于对照组(P<0.05);两组患者的脑卒中复发率、预后良好占比、药品不良反应发生率比较差异均无统计学意义(P>0.05).结论 临床药师实施的系统药学科普干预可显著提高缺血性脑卒中患者出院后的用药依从性,为二级预防措施的有效实施提供重要支撑.
Objective To evaluate the clinical value of clinical pharmacists'pharmaceutical science popularization intervention in secondary prevention for patients with ischemic stroke.Methods A total of 222 patients with acute ischemic stroke who were hospitalized at Qingyuan People's Hospital from February 2024 to April 2025 were selected as research subjects.They were randomly divided into control group(118 cases)and intervention group(104 cases).The control group received routine health education from medical staff,while the intervention group received additional systematic pharmaceutical science popularization interventions provided by clinical pharmacists.The medication compliance,stroke recurrence rate,modified Rankin scale score,and incidence of adverse drug reactions of two groups of patients were compared at 1 month and 6 months after discharge.Results One month and six months after discharge,the medication compliance of patients in intervention group was significantly better than that of control group(P<0.05).There were no statistically significant differences in stroke recurrence rate,the proportion of good prognosis,and the incidence of adverse drug reactions between two groups of patients(P>0.05).Conclusion The systematic pharmaceutical science popularization intervention carried out by clinical pharmacists can significantly improve the medication compliance of patients with ischemic stroke after discharge,providing important support for the effective implementation of secondary prevention measures.
邓惠容;邓桂芳;李思苇;成凤英;张莹;常惠礼
广州医科大学附属清远医院(清远市人民医院)药学部,广东 清远 511518广州医科大学附属清远医院(清远市人民医院)神经内科一区,广东 清远 511518广州医科大学附属清远医院(清远市人民医院)神经内科一区,广东 清远 511518广州医科大学附属清远医院(清远市人民医院)药学部,广东 清远 511518广州医科大学附属清远医院(清远市人民医院)药学部,广东 清远 511518广州医科大学附属清远医院(清远市人民医院)药学部,广东 清远 511518
医药卫生
药学科普缺血性脑卒中二级预防临床药师
Pharmaceutical science popularizationIschemic strokeSecondary preventionClinical pharmacist
《中国现代医生》 2026 (22)
9-12,48,5
广东省药学会科学研究基金项目(2023KP84)
评论