基于复杂网络分析针灸治疗卒中后抑郁的临床应用规律OA

Objective To analyze the core acupoint prescriptions and clinical application law of acupuncture in the treatment of post-stroke depression(PSD)based on complex network analysis.Methods Literature about acupuncture and moxibustion for the treatment of PSD was retrieved from databases including CNKI,Wanfang Data,VIP,Web of Science,and PubMed from their inception to January 1,2026.After screening based on inclusion and exclusion criteria,relevant information was extracted.A descriptive summary was conducted for acupoint frequency,meridian tropism,body regions,specific acupoints,intervention methods,and specialized acupuncture techniques.Association rule analysis for main acupoints was performed using the Apriori algorithm in IBM SPSS Modeler 18.0.OriginPro2026 software was used for clustering analysis,while Cytoscape 3.10.0 software was used for visualization of the main acupoints and syndrome classification-matching acupoints.Results A total of 397 articles were included,yielding 672 prescriptions involving 234 acupoints(including characteristic acupuncture zones),with a total frequency of 3 338 times.The top 10 high-frequency acupoints were Baihui(GV20),Neiguan(PC6),Taichong(LR3),Sanyinjiao(SP6),Shenmen(HT7),Yintang(EX-HN3),Sishencong(EX-HN1),Shenting(GV24),Zusanli(ST36),and Hegu(LI4).Acupoints predominantly belonged to the Governor Vessel and the bladder meridian of foot-taiyang.The head/neck and lower limb regions were most commonly used.Intersection points and Five-Shu acupoints were the primary specific acupoint categories.Acupuncture combined with Western medicine was the main intervention for PSD in clinical practice.Among characteristic acupuncture therapies,scalp acupuncture,ear acupuncture,and eye acupuncture were used most frequently.Association rule analysis indicated the highest support for the combinations of Baihui-Neiguan,Baihui-Taichong-Neiguan,Neiguan-Shenmen-Taichong-Baihui,and Taichong-Yintang-Shenmen-Neiguan-Baihui.Clustering analysis grouped acupoints with a frequency>20 into 6 categories.The main syndromes were liver qi stagnation syndrome,heart-spleen deficiency syndrome,qi stagnation transforming into fire syndrome,phlegm-qi stagnation syndrome,yin deficiency with effulgent fire syndrome,melancholy injuring the spirit syndrome,liver-kidney yin deficiency syndrome,and liver-kidney depletion syndrome.Conclusion The core acupoint prescriptions of acupuncture and moxibustion for the treatment of PSD consist of Baihui(GV20),Neiguan(PC6),Taichong(LR3),Shenmen(HT7),Yintang(EX-HN3),and Sishencong(EX-HN1).The therapeutic approach emphasizes awakening the brain and calming the spirit,nourishing the heart and soothing the liver,with equal importance placed on physical and psychological aspects.