槲皮素缓解霉菌毒素毒性作用的研究进展OA
Strategies for Mycotoxin Toxicity Neutralisation:a Multi-target Mechanism of Action for Quercetin
目前我国饲料霉菌毒素污染问题较为严重,畜禽摄入此类污染饲料后,会引发多个系统生理功能障碍,进而影响动物的生长发育,对动物养殖业构成巨大风险.饲料中常检测出的霉菌毒素有黄曲霉毒素 B1、玉米赤霉烯酮、赭曲霉毒素 A、T-2 毒素和脱氧雪腐镰刀菌烯醇等,它们严重威胁着畜禽饲料安全.槲皮素作为一种天然抗氧化剂,其抗炎、抗氧化、增强免疫应答等生物活性可缓解霉菌毒素所致的毒性损伤,从而降低动物误食被霉菌毒素污染饲料而造成的经济损失.本文综述了槲皮素对上述几种霉菌毒素所致毒性损伤的缓解作用,为其临床应用于霉菌毒素中毒防治提供了理论依据.
At present,mycotoxin contamination in animal feed is a serious problem in China.Consumption of contaminated feed by livestock and poultry can trigger physiological dysfunction in multiple body systems,hindering animal growth and development,and imposing substantial risks on the livestock and poultry industry.The major mycotoxins prevalent in animal feed include aflatoxin B1,zearalenone,ochratoxin A,T-2 toxin,and deoxynivalenol,all of which compromise feed safety for livestock and poultry.As a natural antioxidant,quercetin exhibits anti-inflammatory,antioxidant,and immunomodulatory activities.It can effectively alleviate the toxic damage induced by mycotoxins and reduce economic losses caused by mycotoxin ingestion in animals.This paper reviews the protective effects of quercetin against the toxic injuries induced by the above-mentioned mycotoxins,aiming to provide a theoretical basis for the practical application of quercetin in the prevention and mitigation of livestock mycotoxin poisoning.
胡玉梅;刘冰雪;闫珂鑫;赵欣楠;吕红明
黑龙江八一农垦大学动物科技学院,黑龙江 大庆 163319黑龙江八一农垦大学动物科技学院,黑龙江 大庆 163319黑龙江八一农垦大学动物科技学院,黑龙江 大庆 163319黑龙江八一农垦大学动物科技学院,黑龙江 大庆 163319黑龙江八一农垦大学动物科技学院,黑龙江 大庆 163319
农业科技
槲皮素霉菌毒素解毒机制饲料安全
QuercetinMycotoxinDetoxification mechanismFeed safety
《中国畜牧杂志》 2026 (9)
62-68,7
国家自然科学基金青年项目(32202862)黑龙江八一农垦大学三纵科研支持计划青创人才项目(ZRCQC202305)黑龙江省自然科学基金省市联合指导项目(LH2022C066)
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