山羊绒生长与毛囊发育分子调控机制研究进展OA

Cashmere growth exhibits distinct seasonal periodicity,intrinsically linked to the cyclical activity and developmental progression of secondary hair follicles(SHFs).The hair follicle cycle comprises three defined phases:anagen(growth),catagen(regression),and telogen(quiescence).In cashmere goats,SHFs complete one full cycle annually,a process precisely orchestrated by the photoperiod-melatonin axis.This neuroendocrine pathway drives SHF regeneration by reciprocally activating Wnt/β-catenin signaling while suppressing BMP/Smad transduction cascades.This review article summarizes the cashmere growth dynamics,follicular morphogenesis,and regulatory mechanisms,elucidating the circannual patterning of cashmere growth and the central regulatory role of the photoperiod-melatonin axis in governing follicular cycling.These insights provide a mechanistic framework for enhancing cashmere yield and quality traits in cashmere goats,thereby facilitating sustainable advancement of the cashmere industry.