腰椎术后佩戴腰围对椎体骨密度及螺钉稳定性的影响OA
Clinical effects of lumbar brace on bone mineral density and screw stability after lumbar spinal surgery
目的:分析腰椎退行性疾病内固定术后佩戴腰围对患者椎体骨密度(bone mineral density,BMD)及螺钉稳定性的影响.方法:前瞻性纳入2021年1月1日至2023年12月31日行腰椎后路减压植骨融合内固定术的123例腰椎退行性疾病患者.采用随机数字表法,按术后腰围佩戴时间将患者分为两组:佩戴1个月组70例,其中男20例,女50例,年龄(63.4±7.9)岁;佩戴3个月组53例,其中男18例,女35例,年龄(64.3±7.5)岁.为深入分析骨质疏松状态对结局的影响,依据术前骨密度结果,在随机分组基础上进一步将全部患者划分为骨质疏松亚组54例与非骨质疏松亚组69例.所有患者于术前及术后1、3、6个月接受腰椎CT平扫,使用Bone's FRAX V 1.0软件定量测量椎体骨密度并评估螺钉稳定性,以比较不同佩戴时长及不同骨密度状态下的时序性变化.术前及末次随访,采用视觉模拟评分(visual analogue scale,VAS)进行疼痛评分,采用 Oswestry 功能障碍指数(Oswestry disability index,ODI)进行功能障碍评价.结果:所有患者随访6个月.不论是骨质疏松还是非骨质疏松患者,佩戴1个月组术后3、6个月椎体BMD均高于同期佩戴3个月组(P<0.05);佩戴3个月组术后3、6个月BMD丢失量均大于佩戴1个月组,差异有统计学意义(P<0.05).两组影像学观察螺钉松动率均较高,但无临床症状产生.不论是骨质疏松还是非骨质疏松患者,佩戴1个月组和佩戴3个月组螺钉松动率比较,差异均无统计学意义(P>0.05).末次随访时,佩戴1个月组的腰痛VAS由术前的(7.05±1.08)分降至(2.90±1.02)分,佩戴3个月组由术前(7.19±0.91)分降至(2.83±0.95)分,两组比较差异无统计学意义(P=0.699).末次随访时,佩戴1个月组的ODI由术前(39.69±15.12)分降至(13.08±8.06)分,佩戴3个月组由术前(37.78±14.62)分降至(12.79±8.02)分,两组比较差异无统计学意义(P=0.520).结论:腰椎退行性疾病患者术后佩戴3个月腰围比佩戴1个月腰围丢失的BMD更多且更快.但不同腰围佩戴时间、不同骨质疏松状况对术后螺钉稳定性的影响无明显差异.
Objective To analyze the effect of wearing a lumbar corset after internal fixation surgery for lumbar degenera-tive diseases on patients' vertebral bone mineral density(BMD)and screw stability.Methods A total of 123 patients with lum-bar degenerative diseases who underwent posterior lumbar decompression,bone grafting,fusion,and internal fixation from Jan-uary 1,2021 to December 31,2023 were prospectively enrolled.Using a random number table method,patients were divided into two groups according to the postoperative lumbar corset wearing time:70 cases in the 1-month wearing group 70 cases,in-cluding 20 males and 50 females,aged(63.4±7.9)years;and 50 cases in the 3-month wearing group,including 18 males and 35 females,aged(64.3±7.5)years.To deeply analyze the impact of osteoporosis status on outcomes,all patients were further divided into an osteoporosis subgroup(54 cases)and a non-osteoporosis subgroup(69 cases)based on preoperative bone mineral density results following the initial randomization.All patients underwent plain lumbar CT scans preoperatively and at 1,3,and 6 months postoperatively.Bone's FRAX V1.0 software was used to quantitatively measure vertebral bone mineral density and assess screw stability,aiming to compare the temporal changes under different wearing durations and different bone mineral density states.Preoperatively and at the final follow-up,the visual analogue scale(VAS)was used for pain scoring,and the Oswestry disability index(ODI)was used for dysfunction evaluation.Results All patients were followed up for 6 months.Regardless of whether they were osteoporotic or non-osteoporotic,the vertebral BMD of patients in the 1-month group was sig-nificantly higher than that of patients in the 3-month group at the 3rd and 6th months postoperatively(P<0.05);the BMD loss in the 3-month group was greater than that in the 1-month group at 3 and 6 months postoperatively(P<0.05).In addition,al-though the imaging-observed screw loosening rates were relatively high in both the 1-month and 3-month groups,no clinical symptoms occurred.Whether in osteoporotic or non-osteoporotic patients,there was no statistically significant difference in screw loosening rates between the 1-month and 3-month groups(P>0.05).At the final follow-up,the VAS for low back pain in the 1-month group decreased from(7.05±1.08)preoperatively to(2.90±1.02),while that in the 3-month group decreased from(7.19±0.91)preoperatively to(2.83±0.95),with no statistically significant difference between the two groups at the final follow-up(P=0.699).At the final follow-up,the ODI in the 1-month group decreased from(39.69±15.12)preoperatively to(13.08±8.06),while that in the 3-month group decreased from(37.78±14.62)preoperatively to(12.79±8.02),with no statistically sig-nificant difference between the two groups at the final follow-up(P=0.520).Conclusion Patients with lumbar degenerative dis-eases lose more and faster vertebral BMD when wearing a lumbar corset for 3 months postoperatively compared to wearing it for only 1 month.However,different corset wearing durations and different osteoporosis statuses have no significant impact on postoperative screw stability.
孙伯林;刘家明;陈炜城;熊绪;刘宇;杜浏学;陈宣银;周荣平;黄山虎;刘志礼
南昌大学第一附属医院骨科,江西 南昌 330006||鄂州市中心医院,湖北 鄂州 436000南昌大学第一附属医院骨科,江西 南昌 330006||脊柱脊髓系统疾病江西省重点实验室,江西 南昌 330006||南昌大学脊柱脊髓研究所,江西 南昌 330006南昌大学第一附属医院骨科,江西 南昌 330006||南昌大学第一临床医学院,江西 南昌 330100南昌大学第一附属医院骨科,江西 南昌 330006||联勤保障部队第九〇八医院骨科,江西 南昌 330001南昌大学第一附属医院骨科,江西 南昌 330006||脊柱脊髓系统疾病江西省重点实验室,江西 南昌 330006南昌大学第一附属医院骨科,江西 南昌 330006||脊柱脊髓系统疾病江西省重点实验室,江西 南昌 330006||南昌大学脊柱脊髓研究所,江西 南昌 330006南昌大学第一附属医院骨科,江西 南昌 330006||脊柱脊髓系统疾病江西省重点实验室,江西 南昌 330006||南昌大学脊柱脊髓研究所,江西 南昌 330006南昌大学第一附属医院骨科,江西 南昌 330006||脊柱脊髓系统疾病江西省重点实验室,江西 南昌 330006||南昌大学脊柱脊髓研究所,江西 南昌 330006南昌大学第一附属医院骨科,江西 南昌 330006||脊柱脊髓系统疾病江西省重点实验室,江西 南昌 330006||南昌大学脊柱脊髓研究所,江西 南昌 330006南昌大学第一附属医院骨科,江西 南昌 330006||脊柱脊髓系统疾病江西省重点实验室,江西 南昌 330006||南昌大学脊柱脊髓研究所,江西 南昌 330006
医药卫生
腰椎退行性疾病脊柱融合术内固定器骨密度支具
Lumbar degenerative diseaseSpinal fusionInternal fixatorBone mineral densityBraces
《中国骨伤》 2026 (8)
778-785,8
江西省卫健委科技计划项目(编号:202410014)江西省重点研发计划项目(编号:20252BCG330016)Science and Technology Plan Project of Jiangxi Provincial Health Commission(No.202410014)
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