1例金黄色葡萄球菌全身播散性感染患儿的药学监护OA

Objective To explore the pharmaceutical care provided by clinical pharmacists for pediatric patient with osteomyelitis,pneumonia,and central nervous system involvement caused by hematogenous Staphylococcus aureus(SA)bloodstream infections.Methods Clinical pharmacists were actively involved in the diagnosis and treatment of a 13-year-old male pediatric patient with disseminated systemic SA infection.Anti-infective therapy was optimized via therapeutic drug monitoring(TDM)and pharmacokinetic/pharmacodynamic(PK/PD)analysis of antibiotics at infection sites,and pharmacists collaborated with clinicians to develop individualized treatment plans.Results The physician implemented the pharmacist's recommendations.The patient's infection was satisfactorily controlled without obvious adverse drug reactions,resulting in successful hospital discharge.Conclusion By providing comprehensive pharmaceutical care throughout the entire treatment course for patients with severe infections,clinical pharmacists ensured the therapeutic efficacy and safety of antimicrobial therapy,serving as a critical safeguard for clinical outcomes.