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1例多重病原感染支气管肺炎患儿的药学监护OA

Pharmaceutical Care for a Pediatric Patient with Bronchopneumonia Caused by Multiple Pathogens

中文摘要英文摘要

目的 探讨临床药师对多重病原感染所致支气管肺炎患儿的药学监护.方法 临床药师对 1 例由耐药菌等多重病原体感染所致支气管肺炎患儿的治疗过程实施全流程药学监护,基于循证医学证据进行文献分析,结合病原学结果,为医疗团队提供抗菌药物选择及疗程的精准建议,保障用药的安全性、有效性与经济性.结果 医师采纳建议加用头孢替安后,患儿病情好转.药师对仅基于二代测序技术结果便启用氟康唑的合理性进行了审慎评估,建议未被医师采纳.结论 临床药师及时识别并解决了患儿使用抗菌药物过程中存在的治疗间隙问题,同时基于二代测序技术的方法学局限,建议以动态监测替代即刻抗真菌治疗,体现了保障抗感染方案连续性与避免过度治疗的双重专业价值.

Objective To investigate the pharmaceutical care provided by clinical pharmacists for a child with bronchopneumonia caused by multiple pathogens.Methods Clinical pharmacists delivered whole-process pharmaceutical care for a child with bronchopneumonia attributed to multiple pathogens,including drug-resistant bacteria.Based on clinical evidence,literature analysis,and in conjunction with etiological findings,precise recommendations regarding the selection and duration of antimicrobial therapy were proposed to the medical team,aiming to ensure the safety,efficacy,and cost-effectiveness of medication.Results After the physician adopted the recommendation to add cefotiam,the child's condition improved significantly.The pharmacist prudently evaluated the rationality of initiating fluconazole solely based on next-generation sequencing results,but this recommendation was not adopted by the physician.Conclusion The clinical pharmacist promptly identified and bridged a treatment gap in the child's antibiotic therapy,and considering the methodological limitations of next-generation sequencing,recommended dynamic monitoring instead of immediate antifungal therapy,thereby demonstrating the dual professional value of maintaining the continuity of the anti-infective regimen while avoiding overtreatment.

王璇璇;程虹

武汉大学中南医院药学部,武汉 430071武汉大学中南医院药学部,武汉 430071

医药卫生

支气管肺炎临床药师药学监护

BronchopneumoniaClinical pharmacistPharmaceutical care

《医药导报》 2026 (9)

1517-1523,7

10.3870/j.issn.1004-0781.2026.09.005

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