基于潜在剖面分析的青光眼患者积极度相关因素研究OA

Objective:To explore and analyze the latent profiles of glaucoma patient activation and their associated factors,providing empirical evidence for developing precise clinical intervention strategies.Methods:A cross-sectional survey was conducted,involving 202 glaucoma patients recruited from Zhongshan Ophthalmic Center,Sun Yat-sen University,between July and October 2024.The study utilized the General Information Questionnaire,the Patient Activation Measure,the General Self-Efficacy Scale,and the Perceived Social Support Scale.Latent profile analysis was performed using Mplus 8.3 software to identify distinct profiles of patient activation,and a multivariate regression model was employed to explore the sociodemographic,disease-related,and psychosocial factors associated with different profiles.Results:The patient activation in glaucoma patients was categorized into two latent profiles:"High Activation-Active Adaptation Type"(33.66%)and"Low Activation-Coping Dependent Type"(66.34%).Multivariate analysis revealed that patients who were urban residents,had higher monthly income,presented with advanced visual field defects,underwent three or more surgeries,reported higher general self-efficacy,and had better perceived social support were more likely to belong to the"High Activation-Active Adaptation Type"(P<0.05).Conclusions:The overall level of patient activation in glaucoma patients is moderate to low,predominantly characterized by the"Low Activation-Coping Dependent Type."This suggests that healthcare professionals should prioritize the assessment of patient activation in glaucoma care.Based on the identified latent profiles and their associated factors,personalized and targeted intervention strategies—such as enhancing self-efficacy,expanding social support,and strengthening health education—should be developed for different patient subtypes.These efforts are essential to effectively improve patient activation levels and disease self-management capabilities,thereby enhancing long-term treatment adherence and quality of life.