五门十变配穴理论指导下小儿推拿联合糠酸莫米松鼻喷雾剂治疗儿童过敏性鼻炎临床研究OA
Clinical Study on Pediatric Tuina Combined with Mometasone Furoate Nasal Spray in Treating Pediatric Allergic Rhinitis Guided by the Five Gates and Ten Transformations Point Selection Theory
目的:观察五门十变配穴理论指导下小儿推拿联合糠酸莫米松鼻喷雾剂治疗儿童过敏性鼻炎(AR)的疗效.方法:选取2024年1-8月余姚市人民医院收治的90例AR患儿,按随机数字表法分为常规组及推拿组各45例.常规组给予糠酸莫米松鼻喷雾剂治疗,推拿组在常规组基础上增加五门十变配穴理论指导下小儿推拿.比较2组临床疗效,比较2组治疗前、治疗2周、治疗4周、治疗后3个月的鼻部症状综合情况[鼻部症状总分表(TNSS)、鼻部伴随症状总分表(TNNSS)]、中医证候评分、鼻结膜炎生命质量调查问卷(RQLQ)评分及炎症指标值[嗜酸性粒细胞计数(EOS)、白细胞介素-17(IL-17)]的变化.结果:推拿组临床疗效总有效率为86.67%(39/45),常规组为66.67%(30/45),2组比较,差异有统计学意义(P＜0.05).治疗2周、治疗4周及治疗后3个月,2组TNSS、TNNSS评分均较治疗前下降(P＜0.05),推拿组TNSS、TNNSS评分均低于同一时间段的常规组(P＜0.05).治疗2周、4周及治疗后3个月,2组中医证候评分均较治疗前下降(P＜0.05),推拿组中医证候评分均低于同一时间段的常规组(P＜0.05).治疗2周、4周及治疗后3个月,2组RQLQ评分均较治疗前下降,推拿组RQLQ评分均低于同一时间段的常规组(P＜0.05).治疗2周、4周及治疗后3个月,2组EOS、IL-17水平均较治疗前下降(P＜0.05),推拿组EOS、IL-17水平均低于同一时间段的常规组(P＜0.05).结论:五门十变配穴理论指导下小儿推拿联合糠酸莫米松鼻喷雾剂治疗儿童AR疗效较好,能缓解AR相关症状,降低炎症反应,改善患儿生活质量.
Objective:To observe the efficacy of pediatric tuina combined with Mometasone Furoate Nasal Spray in treating pediatric allergic rhinitis(AR).guided by the five gates and ten transformations point selection theory Methods:A total of 90 children with AR admitted to The People's Hospital of Yuyao from January to August 2024 were selected and randomly divided into a conventional group and a tuina group using the random number table method,with 45 cases in each group.The conventional group received Mometasone Furoate Nasal Spray,while the tuina group received additional pediatric tuina guided by the five gates and ten transformations point selection theory based on the conventional group's regimen.Clinical efficacy was compared between the two groups.Changes in nasal symptom assessment[Total Nasal Symptom Score(TNSS)and Total Non-Nasal Symptom Score(TNNSS)],traditional Chinese medicine syndrome scores,Rhinoconjunctivitis Quality of Life Questionnaire(RQLQ)scores,and inflammatory indicators[eosinophil count(EOS)and interleukin-17(IL-17)]were compared before treatment,after two weeks and four weeks of treatment,and at three months after treatment.Results:The total effective rate was 86.67%(39/45)in the tuina group,significantly higher than that of 66.67%(30/45)in the conventional group(P＜0.05).TNSS and TNNSS scores decreased in both groups at two weeks,four weeks,and three months after treatment compared to before treatment(P＜0.05),with lower scores in the tuina group at all time points(P＜0.05).Traditional Chinese medicine syndrome scores decreased in both groups at all time points(P＜0.05),with lower scores in the tuina group(P＜0.05).RQLQ scores decreased in both groups at all time points(P＜0.05),with lower scores in the tuina group(P＜0.05).EOS and IL-17 levels decreased in both groups at all time points(P＜0.05),with lower levels in the tuina group(P＜0.05).Conclusion:Pediatric tuina combined with Mometasone Furoate Nasal Spray guided by the five gates and ten transformations point selection theory demonstrates good efficacy in treating pediatric AR.It alleviates AR-related symptoms,reduces inflammatory responses,and improves the quality of life of affected children.
闻君;范益辉;詹晓庆;王咪娜
宁波大学附属阳明医院/余姚市人民医院,浙江 余姚 315400宁波大学附属阳明医院/余姚市人民医院,浙江 余姚 315400宁波大学附属阳明医院/余姚市人民医院,浙江 余姚 315400宁波大学附属阳明医院/余姚市人民医院,浙江 余姚 315400
医药卫生
过敏性鼻炎儿童五门十变配穴小儿推拿糖皮质激素
Allergic rhinitisChildrenFive gates and ten transformations point selectionPediatric tuinaGlucocorticoids
《新中医》 2026 (17)
51-56,6
余姚市科技计划项目(2024YZYB03)
评论