大青龙汤的古代文献考证与现代临床应用分析OACHSSCD
Historical Evolution and Modern Clinical Applications of Daqinglong Decoction
本研究采用文献考证法对大青龙汤的方剂名称与出处、组成和剂量演变、基原与炮制方法、煎煮工艺、古代应用、现代应用等方面进行了系统考证.考证结果表明,大青龙汤最早记载于《伤寒论》和《金匮要略》,由麻黄、桂枝、甘草、杏仁、生姜、大枣、石膏七味药材组成,具有发汗解表,兼清里热的作用.方中"炙甘草"应为"炒甘草",其余药物均为常规处理后的生品.七味药材基原与2025 年版《中华人民共和国药典》记载一致.经考证,《伤寒论》和《金匮要略》中大青龙汤的剂量折合成现代剂量为麻黄82.8 g、桂枝27.6 g、甘草27.6 g、杏仁14.8 g、生姜41.4 g、大枣30 g、石膏90 g.该方剂具有发汗解表,兼清里热之效,主要用于治疗呼吸科、儿科、肾病科、皮肤科、神经内科相关疾病.大青龙汤方应用前景广泛,值得进一步深入研究和开发.
This study systematically investigated Daqinglong Decoction using literature-based textual research,focusing on its for-mula name and origin,compositional and dosage evolution,medicinal material origins and processing methods,decoction proce-dures,ancient applications,and modern applications.The results showed that Daqinglong Decoction was first recorded in Treatise on Cold Damage Diseases(Shanghan Lun)and Synopsis of the Golden Chamber(Jin Kui Yao Lue).The formula consists of seven me-dicinal materials,i.e.,Ephedrae Herba,Cinnamomi Ramulus,Glycyrrhizae Radix et Rhizoma Praeparata cum Melle,Armeniacae Semen Amarum,Zingiberis Rhizoma Recens,Jujubae Fructus,and Gypsum Fibrosum.It exerts the effects of inducing sweating to release the exterior and clearing interior heat.In the original formula,Glycyrrhizae Radix et Rhizoma Praeparata cum Melle should be prepared by stir-frying,while the other medicinal materials are all crude drugs after routine processing.The origins of the seven medicinal materials are consistent with those recorded in the Pharmacopoeia of the People's Republic of China(2025 edition).Ac-cording to textual research,the dosages of Daqinglong Decoction recorded inTreatise on Cold Damage Diseases and Synopsis of the Golden Chamber are converted into modern equivalents as follows:Ephedrae Herba 82.8 g,Cinnamomi Ramulus 27.6 g,Glycyrrhi-zae Radix et Rhizoma Praeparata cum Melle 27.6 g,Armeniacae Semen Amarum 14.8 g,Zingiberis Rhizoma Recens 41.4 g,Ju-jubae Fructus 30 g,and Gypsum Fibrosum 90 g.This formula has the effects of inducing sweating to release the exterior and clear-ing interior heat,and is mainly used for diseases related to pulmonology,pediatrics,nephrology,dermatology,and neurology.Daqin-glong Decoction has broad application prospects and warrants further in-depth research and development.
邬一弘;张宏;杨舒淇;孟儒;刘柏言;朱坤;尤耀东
成都中医药大学,成都,611137||成都中医药大学附属医院,成都,610075成都中医药大学,成都,611137||成都中医药大学附属医院,成都,610075成都中医药大学,成都,611137||成都中医药大学养生康复学院,成都,611137成都中医药大学,成都,611137||成都中医药大学附属医院,成都,610075成都中医药大学,成都,611137||成都中医药大学附属医院,成都,610075成都中医药大学,成都,611137||成都中医药大学附属医院,成都,610075成都中医药大学,成都,611137||成都中医药大学附属医院,成都,610075
医药卫生
大青龙汤关键信息现代应用文献考证组方基原剂量临床应用
Daqinglong DecoctionKey informationModern applicationsTextual researchFormula compositionPrimary bo-tanical materialsDosage standardizationClinical application
《世界中医药》 2026 (11)
2022-2031,10
国家自然科学基金项目(82374415)四川省中医药管理局科学技术研究专项(2023MS154).
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