赶黄草黄酮提取工艺优化及对黄羽肉鸡生长性能、抗氧化性能、免疫功能及饲养经济效益的影响OA

The experiment aimed to study the extraction process of Penthorum chinense flavonoids and their effects on the growth performance,antioxidant capacity,immune function,and economic benefits of broilers.The response surface methodology was employed to optimize the ultrasonic-assisted ethanol extraction pro-cess for Penthorum chinense flavonoids.Addition-ally,320 21-day-old yellow-feathered broilers were randomly divided into four groups(8 repli-cates per group,with 10 broilers per replicate).Group A(control group)was fed a basal diet,while groups B,C,and D received basal diets supple-mented with 200,400,and 800 mg/kg of Pen-thorum chinense flavonoids,respectively.The pretrial period lasted 7 days,followed by a formal trial period of 21 days.Results showed:① the optimal extraction conditions were and ultrasonic power was 356 W,a temperature of 51℃,and a duration of 36 min,under these conditions,the yield of Penthorum chinense fla-vonoids was 3.86%.② Compared to group A,the final body weight and average daily gain(ADG)of broilers in groups C and D significantly increased(P<0.05),while the feed-to-gain ratio(F/G)significantly decreased(P<0.05).However,there were no significant differences in average daily feed intake(ADFI)among the groups.③ Compared to group A,the glutathione peroxidase(GSH-Px),superoxide dismutase(SOD),total antioxidant capacity(T-AOC),and catalase(CAT)activities in groups C and D significantly increased(P<0.05),while malondialdehyde(MDA)levels significantly decreased(P<0.05).④ Compared to group A,the immunoglobulin G(IgG),immunoglobulin M(IgM),and immunoglobulin A(IgA)levels in groups C and D significantly increased(P<0.05),while tumor necrosis factor-alpha(TNF-α)and interleu-kin-6(IL-6)levels significantly decreased(P<0.05).⑤ Based on feed market prices,broiler selling prices,and Penthorum chinense flavonoids prices,economic benefit formula analysis revealed that compared to the control group,the profits of broiler breeding in groups B,C,and D increased by 2.50%,7.86%,and 15.00%,respectively.These findings indicate that Penthorum chinense flavonoids can improve broiler growth perfor-mance,antioxidant capacity,immune function,and economic benefits.