典型手性有机酸对布洛芬对映体在多孔介质中迁移的影响OA

To investigate the influence of typical chiral organic acids on the transport of ibuprofen enantiomers in porous media.Quartz sand column experiments combined with quantum chemical calculations were conducted to examine the effects of malic acid,tartaric acid,and camphoric acid on the transport behavior of ibuprofen enantiomers.The results showed that pH significantly affected the migration of ibuprofen enantiomers,with higher pH enhancing transport.Chiral organic acids regulated the migration of ibuprofen enantiomers through competitive adsorption and stereoselective interactions,with malic acid exerting the strongest promotion effect and obvious stereoselectivity.Quantum chemical calculations indicated that homochiral interactions exhibited stronger hydrogen bonding and van der Waals forces,leading to enhanced retention of ibuprofen enantiomers in porous media.This study highlights the stereoselective regulation of ibuprofen enantiomer transport by chiral organic acids and suggests that the coexistence of such acids in the environment may induce stereoselective enrichment during transport.