首页|期刊导航|全科护理|冠心病病人PCI术后主要不良心血管事件的危险因素分析及基于老年综合评估与思维导图的护理干预效果研究

冠心病病人PCI术后主要不良心血管事件的危险因素分析及基于老年综合评估与思维导图的护理干预效果研究OA

Risk factors analysis of major adverse cardiovascular events in patients with coronary heart disease after PCI and study on the effect of nursing intervention based on comprehensive geriatric assessment and mind map

中文摘要英文摘要

目的:探讨冠心病(CHD)病人经皮冠状动脉介入治疗(PCI)后发生主要不良心血管事件(MACE)的危险因素,并评估老年综合评估(CGA)联合思维导图式宣教的护理干预效果.方法:选取2023年3月—2024年5月在医院行PCI治疗后的314例CHD病人为研究对象,依据是否发生MACE分为发生组(n=97)和未发生组(n=217).采用Logistic回归分析影响因素并绘制列线图模型,使用受试者工作特征(ROC)曲线、校准曲线、决策曲线评估预测模型.以发生组存活例数为研究对象(n=78),根据干预方式将其分为观察组(n=39)和对照组(n=39),对照组实施常规干预,观察组在对照组的基础上给予CGA+思维导图式的宣教措施,比较两组预后情况.结果:Logistic回归分析结果显示,N端脑钠肽前体(NT-proBNP)>100 pg/mL、左心室后壁厚度(LVPWT)升高、室间隔厚度(IVST)升高、C反应蛋白(CRP)≥5 mg/L、24 h平均舒张压变异性(24 h DBPV)升高、24 h收缩压变异性(24 h SBPV)升高、合并高血压均为影响CHD病人PCI术后发生MACE的独立危险因素(P<0.05).列线图模型显示IVST对病人发生MACE的诊断能力最好;ROC结果显示模型曲线下面积(AUC)为0.932[95%CI(0.902,0.962)];校准曲线和决策曲线提示该模型具有较好的准确率.干预后,观察组下床时间、活动时间、住院时间短于对照组,3个月内再次入院率低于对照组(均P<0.05);观察组心肺功能指标[左心室射血分数(LVEF)、左心室舒张末期内径(LVEDD)、氧脉搏和无氧阈]和运动耐量(到达运动终点时间、发生运动心绞痛例数、最大心率、运动试验阳性例数)优于对照组(均P<0.05);观察组Barthel指数(BI)评分、心血管健康行为评分(CHS)均高于对照组(P<0.05).结论:NT-proBNP>100 pg/mL、LVPWT升高、IVST升高、CRP≥5 mg/L、24 h DBPV升高、24 h SBPV升高、合并高血压均为影响CHD病人PCI后发生MACE的独立危险因素,且均具有预测价值.实施CGA联合思维导图式宣教的护理模式可有效加快病人康复进程,改善病人预后情况.

Objective:To investigate the risk factors for major adverse cardiovascular events(MACE)in patients with coronary heart disease(CHD)after percutaneous coronary intervention(PCI),and to evaluate the intervention effect of nursing care combining comprehensive geriatric assessment(CGA)and mind map-based health education.Methods:A total of 314 CHD patients who received PCI treatment in the hospital from March 2023 to May 2024 were enrolled as study subjects.They were divided into the MACE group(n=97)and the non-MACE group(n=217)according to whether MACE occurred.Logistic regression was used to analyze the influencing factors,and a Nomogram model was constructed.The prediction model was evaluated using the receiver operating characteristic(ROC)curve,calibration curve and decision curve.The surviving patients in the MACE group(n=78)were selected as the study population and divided into the observation group(n=39)and the control group(n=39)according to the intervention mode.The patients in control group received routine intervention,while the patients in observation group were given CGA combined with mind map-based health education on the basis of the control group.The prognosis of the two groups was compared.Results:Logistic regression analysis showed that N-terminal pro-B-type natriuretic peptide(NT-proBNP)>100 pg/mL,increased left ventricular posterior wall thickness(LVPWT),increased interventricular septal thickness(IVST),C-reactive protein(CRP)≥5 mg/L,increased 24-hour mean diastolic blood pressure variability(24 h DBPV),increased 24-hour systolic blood pressure variability(24 h SBPV),and complicated hypertension were all independent risk factors for MACE in CHD patients after PCI(P<0.05).The Nomogram model indicated that IVST had the best diagnostic performance for MACE in patients.ROC results showed that the area under the curve(AUC)of the model was 0.932[95%CI(0.902,0.962)].The calibration curve and decision curve suggested that the model had favorable accuracy.After intervention,the time to get out of bed,activity time and hospital stay in the observation group were shorter than those in the control group,and the 3-month readmission rate was lower than that in the control group(all P<0.05).The cardiopulmonary function indexes[left ventricular ejection fraction(LVEF),left ventricular end-diastolic diameter(LVEDD),oxygen pulse and anaerobic threshold]and exercise tolerance(time to reach exercise endpoint,number of cases with exercise-induced angina pectoris,maximum heart rate,number of positive exercise test cases)in the observation group were better than those in the control group(all P<0.05).The Barthel Index(BI)score,Cardiovascular Health Behavior Score(CHS)score in the observation group were all higher than those in the control group(P<0.05).Conclusions:NT-proBNP>100 pg/mL,increased LVPWT,increased IVST,CRP≥5 mg/L,increased 24 h DBPV,increased 24 h SBPV and complicated hypertension are all independent risk factors for MACE in CHD patients after PCI,and all have predictive value.The nursing model of CGA combined with mind map-based health education can effectively accelerate the rehabilitation process and improve the prognosis of patients.

段慧玲;王金萍

200434,海军军医大学第一附属医院200434,海军军医大学第一附属医院

冠心病经皮冠状动脉介入治疗主要不良心血管事件预后老年综合评估思维导图

coronary heart disease,CHDpercutaneous coronary intervention,PCImajor adverse cardiovascular events,MACEprognosiscomprehensive geriatric assessment,CGAmind map

《全科护理》 2026 (18)

3415-3421,7

10.12104/j.issn.1674-4748.2026.18.005

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