基于"六经伏毒"理论动态调节原发性肝癌免疫稳态思路OA

The disease process of primary liver cancer(PLC)is closely related to the immune state imbalance led by immune editing,and the above dynamic process is highly consistent with the theory of transmission and transformation of the six meridians in traditional Chinese medicine.Accordingly,Professor Hou Aihua puts forward the idea of dynamically adjusting PLC immune homeostasis based on the theory of"latent toxins in the six channels",and establishes a PLC immune homeostasis regulation system combining disease differentiation and syndrome differentiation,so as to control the transmission of pathogens,rectify the staged immune unbalanced state and cut off immune editing.Professor Hou Aihua,based on the pathological characteristics of primary liver cancer such as adhering and lingering"dampness,heat,blood stasis and toxin",proposes the core treatment approaches for PLC on the basis of disease differentiation,such as invigorating the spleen,tonifying the kidney and nourishing the liver,detoxifying and removing blood stasis and softening hard masses.Furthermore,he further comes up with the ideas for syndrome differentiation and treatment of immune imbalance in PLC at different stages from the perspective of the"six meridians laten toxins"theory.In the early subclinical stage,his treatment prioritizes harmonizing yingfen and weifen,and restoring smooth flow of the pivot qi.In the sub-clinical stage,his treatment is aimed at harmonizing shaoyang,soothing the liver and regulating qi.In the advanced stage,his treatment is targeted at detoxifying and softening hard masses,and clearing yangming.In the remission stage,his treatment underlines dispersing the liver and strengthening the spleen,resolving blood stasis and softening hard masses.In the final stage,his treatment is advisable to nourish the liver and kidney,detoxify and eliminate hard masses.His core prescription features Yugan Sanjie Decoction based on disease differentiation,paired with classic formulas based on the syndrome differentiation of six channels.