基于窠囊理论论析类风湿肺结节病机与治疗OA

Pulmonary involvement occurs in 60%-80%of patients with rheumatoid arthritis(RA),manifesting as a wide spectrum of respiratory disorders.Rheumatoid pulmonary nodules,a distinct pulmonary manifestation of RA,pose considerable therapeutic challenges.Currently,the management for these lesions primarily focuses on controlling the progression of rheumatoid arthritis,and specific targeted therapies remain lacking.Clinically and pathogenically,rheumatoid pulmonary nodules closely resemble the concept of Ke-nang in traditional Chinese medicine(TCM),which predominantly affects the lung and is characterized by the intermingling of phlegm,qi stagnation,and blood stasis.This study elucidates the pathogenesis and therapeutic strategies of rheumatoid pulmonary nodules through the lens of Ke-nang theory,with the aim of identifying novel therapeutic targets and providing new insights to guide clinical practice.